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4IDY

Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with 2-hydroxyethyl disulfide

Functional Information from GO Data
ChainGOidnamespacecontents
A0004177molecular_functionaminopeptidase activity
A0004239molecular_functioninitiator methionyl aminopeptidase activity
A0005506molecular_functioniron ion binding
A0005829cellular_componentcytosol
A0006508biological_processproteolysis
A0008235molecular_functionmetalloexopeptidase activity
A0016485biological_processprotein processing
A0046872molecular_functionmetal ion binding
A0050897molecular_functioncobalt ion binding
A0070006molecular_functionmetalloaminopeptidase activity
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE HED A 301
ChainResidue
ATHR94
ACYS105
AHIS114
AASP131
AVAL132
ATHR133
AASP142
APHE211
ATRP255

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE K A 302
ChainResidue
ASER107
ALEU108
AASN109
AVAL111
ATHR265
AHOH466

Functional Information from PROSITE/UniProt
site_idPS00680
Number of Residues19
DetailsMAP_1 Methionine aminopeptidase subfamily 1 signature. FtGHGIGttfHnglvVl.HY
ChainResidueDetails
APHE202-TYR220

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues7
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01974, ECO:0000269|PubMed:15882055, ECO:0000269|PubMed:20038112, ECO:0000269|PubMed:21465667
ChainResidueDetails
AHIS114
AASP131
AASP142
AHIS205
AHIS212
AGLU238
AGLU269

227111

PDB entries from 2024-11-06

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