Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4IDQ

human atlastin-1 1-446, N440T, GDPAlF4-

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GDP A 501

Chain	Residue
A	ARG77
A	ARG217
A	ASP218
A	PRO272
A	VAL276
A	ALF502
A	MG503
A	HOH601
A	HOH604
A	HOH609
A	HOH655
A	LYS78
A	HOH761
A	HOH780
B	HOH779
A	GLY79
A	LYS80
A	SER81
A	PHE82
A	TRP112
A	ARG113
A	GLY114

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ALF A 502

Chain	Residue
A	PHE76
A	ARG77
A	LYS80
A	ARG118
A	GLU119
A	THR120
A	GLY149
A	GDP501
A	MG503
A	HOH601
A	HOH605

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 503

Chain	Residue
A	SER81
A	THR120
A	GDP501
A	ALF502
A	HOH601
A	HOH604

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE P6G A 504

Chain	Residue
A	ASN355
A	ALA359
A	THR362
A	VAL405
A	LYS406
A	HOH708
A	HOH714
B	GLU339
B	GLU340
B	LEU341

site_id	AC5
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GDP B 501

Chain	Residue
B	ARG77
B	LYS78
B	GLY79
B	LYS80
B	SER81
B	PHE82
B	TRP112
B	ARG113
B	GLY114
B	ARG217
B	ASP218
B	HIS271
B	PRO272
B	VAL276
B	PHE282
B	ALF502
B	MG503
B	HOH601
B	HOH603
B	HOH685
B	HOH755
B	HOH761
B	HOH783

site_id	AC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ALF B 502

Chain	Residue
B	PHE76
B	ARG77
B	LYS80
B	ARG118
B	GLU119
B	THR120
B	THR147
B	GLY149
B	GDP501
B	MG503
B	HOH601
B	HOH604

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 503

Chain	Residue
B	SER81
B	THR120
B	GDP501
B	ALF502
B	HOH601
B	HOH603

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE P6G B 504

Chain	Residue
A	GLU339
A	GLU340
A	LEU341
A	PRO342
B	ALA358
B	ALA359
B	VAL405
B	LYS406

site_id	AC9
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GDP C 501

Chain	Residue
C	LYS78
C	GLY79
C	LYS80
C	SER81
C	PHE82
C	TRP112
C	ARG113
C	GLY114
C	ARG217
C	ASP218
C	HIS271
C	PRO272
C	VAL276
C	ALF502
C	MG503
C	HOH601
C	HOH603
C	HOH709
C	HOH732
C	HOH753
C	HOH759
C	ARG77

site_id	BC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ALF C 502

Chain	Residue
C	PHE76
C	ARG77
C	LYS80
C	ARG118
C	GLU119
C	THR120
C	THR147
C	GLY149
C	GDP501
C	MG503
C	HOH601
C	HOH604

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 503

Chain	Residue
C	SER81
C	THR120
C	GDP501
C	ALF502
C	HOH601
C	HOH603

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE P6G C 504

Chain	Residue
C	ASN355
C	VAL405
C	LYS406
D	GLU339
D	LEU341
D	PRO342

site_id	BC4
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GDP D 501

Chain	Residue
D	ARG77
D	LYS78
D	GLY79
D	LYS80
D	SER81
D	PHE82
D	TRP112
D	ARG113
D	GLY114
D	ARG217
D	ASP218
D	HIS271
D	PRO272
D	VAL276
D	ALF502
D	MG503
D	HOH601
D	HOH602
D	HOH606
D	HOH666
D	HOH707
D	HOH756
D	HOH764

site_id	BC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ALF D 502

Chain	Residue
D	PHE76
D	ARG77
D	LYS80
D	ARG118
D	GLU119
D	THR120
D	GLY149
D	GDP501
D	MG503
D	HOH602
D	HOH604

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 503

Chain	Residue
D	SER81
D	THR120
D	GDP501
D	ALF502
D	HOH601
D	HOH602

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE P6G D 504

Chain	Residue
C	GLU339
C	LEU341
C	PRO342
C	HIS343
D	ASN355
D	ALA359
D	VAL405
D	LYS406

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	980
Details	Domain: {"description":"GB1/RHD3-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01052","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38509071","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	364
Details	Region: {"description":"3HB (three-helix bundle) domain","evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38509071","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	108
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4IDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IDP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QOF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PDB","id":"6XJN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QOF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6XJN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q6DD88","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)