4IDO

human atlastin-1 1-446, C-his6, GDPAlF4-

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GDP A 501

Chain	Residue
A	ARG77
A	ARG217
A	ASP218
A	HIS271
A	PRO272
A	VAL276
A	ALF502
A	MG503
A	HOH601
A	HOH627
A	HOH656
A	LYS78
A	HOH782
A	HOH920
A	GLY79
A	LYS80
A	SER81
A	PHE82
A	TRP112
A	ARG113
A	GLY114

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ALF A 502

Chain	Residue
A	PHE76
A	ARG77
A	LYS80
A	ARG118
A	GLU119
A	THR120
A	GLY149
A	GDP501
A	MG503
A	HOH697
A	HOH920

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 503

Chain	Residue
A	SER81
A	THR120
A	GDP501
A	ALF502
A	HOH601
A	HOH920

---

site_id	AC4
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GDP B 501

Chain	Residue
A	HOH610
B	ARG77
B	LYS78
B	GLY79
B	LYS80
B	SER81
B	PHE82
B	TRP112
B	ARG113
B	GLY114
B	ARG217
B	ASP218
B	PRO272
B	VAL276
B	PHE282
B	ALF502
B	MG503
B	HOH601
B	HOH616
B	HOH719
B	HOH806
B	HOH938

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ALF B 502

Chain	Residue
B	PHE76
B	ARG77
B	LYS80
B	ARG118
B	GLU119
B	THR120
B	GLY149
B	GDP501
B	MG503
B	HOH789
B	HOH938

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 503

Chain	Residue
B	SER81
B	THR120
B	GDP501
B	ALF502
B	HOH601
B	HOH938

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	490
Details	Domain: {"description":"GB1/RHD3-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01052","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38509071","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	182
Details	Region: {"description":"3HB (three-helix bundle) domain","evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38509071","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	54
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23334294","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"4IDN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IDP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QOF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"6XJN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21220294","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21368113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34546351","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QNU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QOF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6XJN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q6DD88","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	8
Details	Region: {"description":"Linker","evidences":[{"source":"PubMed","id":"38509071","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---