4IDM

Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003842	molecular_function	L-glutamate gamma-semialdehyde dehydrogenase activity
A	0004657	molecular_function	proline dehydrogenase activity
A	0006560	biological_process	proline metabolic process
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0010133	biological_process	L-proline catabolic process to L-glutamate
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00070
Number of Residues	12
Details	ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. FdYQGQKCSAVS

Chain	Residue	Details
A	PHE320-SER331

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site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GETGGKDF

Chain	Residue	Details
A	GLY292-PHE299

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