Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE T27 A 601 |
| Chain | Residue |
| A | LEU100 |
| A | HIS235 |
| A | PRO236 |
| A | TYR318 |
| B | GLU138 |
| B | HOH631 |
| A | LYS101 |
| A | LYS103 |
| A | TYR181 |
| A | TYR188 |
| A | PRO225 |
| A | PHE227 |
| A | TRP229 |
| A | LEU234 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1FE A 602 |
| Chain | Residue |
| A | GLU396 |
| A | THR397 |
| A | THR400 |
| A | LEU425 |
| A | GLN428 |
| A | GLU430 |
| A | DMS606 |
| A | HOH713 |
| A | HOH1020 |
| A | HOH1050 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 603 |
| Chain | Residue |
| A | ASP443 |
| A | ASP498 |
| A | ASP549 |
| A | HOH1060 |
| A | HOH1061 |
| A | HOH1096 |
| A | HOH1097 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 604 |
| Chain | Residue |
| A | ASN363 |
| A | TRP401 |
| A | LEU425 |
| A | TRP426 |
| A | TYR427 |
| A | GLN509 |
| A | HOH863 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DMS A 605 |
| Chain | Residue |
| A | ILE380 |
| A | VAL381 |
| B | PRO25 |
| B | LEU26 |
| B | PRO133 |
| B | SER134 |
| B | ILE135 |
| B | ASN136 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 606 |
| Chain | Residue |
| A | TRP426 |
| A | TYR427 |
| A | GLN428 |
| A | LEU525 |
| A | LYS528 |
| A | GLU529 |
| A | 1FE602 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS A 607 |
| Chain | Residue |
| A | LYS331 |
| A | GLN334 |
| A | LYS512 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS A 608 |
| Chain | Residue |
| A | THR473 |
| A | ASN474 |
| A | GLN475 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS A 609 |
| Chain | Residue |
| A | TYR115 |
| A | LEU149 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 610 |
| Chain | Residue |
| A | LYS238 |
| A | HIS315 |
| A | HOH800 |
| B | VAL317 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 611 |
| Chain | Residue |
| A | ARG463 |
| A | ASP488 |
| A | SER489 |
| A | GLY490 |
| A | HOH856 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 612 |
| Chain | Residue |
| A | ARG277 |
| A | GLN278 |
| A | LYS281 |
| A | ARG356 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 501 |
| Chain | Residue |
| B | THR27 |
| B | THR400 |
| B | TRP401 |
| B | GLU404 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 502 |
| Chain | Residue |
| A | LYS11 |
| A | GLN85 |
| B | TYR56 |
| B | LYS126 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS B 503 |
| Chain | Residue |
| B | LEU234 |
| B | HIS235 |
| B | TRP239 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 504 |
| Chain | Residue |
| B | TRP24 |
| B | GLU399 |
| B | TRP402 |
| B | HOH627 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 505 |
| Chain | Residue |
| A | GLU138 |
| B | GLN269 |
| B | LEU422 |
| B | TRP426 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS B 506 |
| Chain | Residue |
| B | HOH748 |
| B | PRO243 |
| B | ILE244 |
| B | VAL245 |
| B | LYS263 |
| B | TYR427 |
| B | GLN428 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS B 507 |
| Chain | Residue |
| B | GLN242 |
| B | ILE244 |
| B | TYR271 |
| B | ASN348 |
| B | HOH639 |
| B | HOH838 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 190 |
| Details | Domain: {"description":"Reverse transcriptase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"RT 'primer grip'"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Tryptophan repeat motif"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Essential for RT p66/p51 heterodimerization"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by viral protease; partial"} |
