4IBG
Ebola virus VP35 bound to small molecule
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 1D6 A 401 |
| Chain | Residue |
| A | ALA221 |
| A | GOL405 |
| A | HOH589 |
| B | HIS296 |
| B | PO4405 |
| A | GLN241 |
| A | GLN244 |
| A | LYS248 |
| A | LYS251 |
| A | PRO293 |
| A | VAL294 |
| A | ASP302 |
| A | ARG305 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | TYR229 |
| A | GLY236 |
| A | HIS240 |
| A | GLN241 |
| A | GLN244 |
| A | PRO304 |
| A | HOH544 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | HIS296 |
| B | ILE295 |
| B | HIS296 |
| B | 1D6401 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 404 |
| Chain | Residue |
| A | ASP271 |
| A | SER272 |
| A | CYS275 |
| A | ASP332 |
| A | GLY333 |
| A | LYS334 |
| B | ASP252 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | PRO293 |
| A | VAL294 |
| A | 1D6401 |
| A | HOH531 |
| A | HOH553 |
| B | VAL294 |
| B | HIS296 |
| B | GLN329 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 1D6 B 401 |
| Chain | Residue |
| A | HIS296 |
| A | SO4403 |
| B | ALA221 |
| B | GLN241 |
| B | GLN244 |
| B | LYS248 |
| B | LEU249 |
| B | LYS251 |
| B | PRO293 |
| B | ASP302 |
| B | GOL403 |
| B | HOH596 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 402 |
| Chain | Residue |
| B | TYR229 |
| B | GLY236 |
| B | GLN241 |
| B | GLN244 |
| B | PRO304 |
| B | HOH583 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 403 |
| Chain | Residue |
| A | VAL294 |
| A | GLN329 |
| B | PRO293 |
| B | VAL294 |
| B | 1D6401 |
| B | HOH538 |
| B | HOH542 |
| B | HOH566 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 404 |
| Chain | Residue |
| A | ASP252 |
| B | ASP271 |
| B | SER272 |
| B | CYS275 |
| B | ASP332 |
| B | GLY333 |
| B | LYS334 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 B 405 |
| Chain | Residue |
| A | ILE295 |
| A | HIS296 |
| A | 1D6401 |
| B | HIS296 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"PubMed","id":"31562565","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"PubMed","id":"31562565","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31694758","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"28679761","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35533195","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
