4IBD
Ebola virus VP35 bound to small molecule
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1DL A 401 |
| Chain | Residue |
| A | ALA221 |
| A | HOH539 |
| A | HOH603 |
| A | GLN241 |
| A | GLN244 |
| A | LYS248 |
| A | LYS251 |
| A | PRO293 |
| A | ILE295 |
| A | ILE297 |
| A | ARG305 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | ASP271 |
| A | SER272 |
| A | CYS275 |
| A | ASP332 |
| A | LYS334 |
| B | ASP252 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1DL B 401 |
| Chain | Residue |
| B | ALA221 |
| B | GLN241 |
| B | GLN244 |
| B | LYS248 |
| B | LYS251 |
| B | PRO293 |
| B | ASP302 |
| B | HOH566 |
| B | HOH584 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 402 |
| Chain | Residue |
| A | ASP252 |
| B | ASP271 |
| B | SER272 |
| B | CYS275 |
| B | ASP332 |
| B | LYS334 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 403 |
| Chain | Residue |
| B | LEU232 |
| B | PRO233 |
| B | GLY234 |
| B | HOH511 |
| B | HOH582 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by host => ECO:0000269|PubMed:31562565 |
| Chain | Residue | Details |
| A | SER310 | |
| B | SER310 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by host => ECO:0000269|PubMed:31562565, ECO:0000269|PubMed:31694758 |
| Chain | Residue | Details |
| A | SER317 | |
| B | SER317 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:28679761, ECO:0000269|PubMed:35533195 |
| Chain | Residue | Details |
| A | LYS309 | |
| B | LYS309 |
