Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0004674 | molecular_function | protein serine/threonine kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 401 |
| Chain | Residue |
| A | LYS68 |
| A | PHE113 |
| A | ILE174 |
| A | ASP175 |
| A | HOH503 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | LEU45 |
| A | GLY46 |
| A | HIS183 |
| A | HOH573 |
| A | HOH654 |
| A | ASN16 |
| A | THR17 |
| A | ARG43 |
| A | LYS44 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | TYR39 |
| A | ALA98 |
| A | HOH590 |
| A | HOH593 |
| A | HOH607 |
| B | HOH510 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 404 |
| Chain | Residue |
| A | ILE94 |
| A | ILE95 |
| A | THR96 |
| A | GLU114 |
| A | HIS115 |
| A | ARG172 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | ASP156 |
| A | LYS158 |
| A | SER194 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 406 |
| Chain | Residue |
| A | HIS148 |
| A | ALA315 |
| A | HOH517 |
| A | HOH541 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 407 |
| Chain | Residue |
| A | ARG80 |
| A | ARG155 |
| A | HOH528 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 401 |
| Chain | Residue |
| B | ARG47 |
| B | VAL53 |
| B | VAL66 |
| B | LYS68 |
| B | ILE95 |
| B | PHE113 |
| B | ILE174 |
| B | ASP175 |
| B | HOH514 |
| B | HOH600 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 401 |
| Chain | Residue |
| C | LYS49 |
| C | ASP156 |
| C | LYS158 |
| C | SER194 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 402 |
| Chain | Residue |
| C | LYS68 |
| C | ILE174 |
| C | ASP175 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 403 |
| Chain | Residue |
| B | SER194 |
| B | HOH570 |
| C | GLU252 |
| C | ASP256 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 404 |
| Chain | Residue |
| C | HIS148 |
| C | THR314 |
| C | ALA315 |
| C | HOH520 |
| C | HOH544 |
| site_id | BC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR CHAIN D OF CK2BETA-DERIVED CYCLIC PEPTIDE |
| Chain | Residue |
| A | PRO6 |
| A | GLN36 |
| A | TYR39 |
| A | GLN40 |
| A | LEU41 |
| A | GLU52 |
| A | PHE54 |
| A | VAL67 |
| A | ILE69 |
| A | LYS71 |
| A | VAL101 |
| A | ASP103 |
| A | HOH554 |
| A | HOH591 |
| C | TYR146 |
| C | ASP271 |
| D | HOH203 |
| D | HOH204 |
| D | HOH205 |
| D | HOH206 |
| site_id | BC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR CHAIN E OF CK2BETA-DERIVED CYCLIC PEPTIDE |
| Chain | Residue |
| B | GLN36 |
| B | TYR39 |
| B | GLN40 |
| B | LEU41 |
| B | GLU52 |
| B | ILE57 |
| B | ILE69 |
| B | VAL101 |
| B | ASP103 |
| B | HOH509 |
| C | PRO322 |
| C | TYR325 |
| C | LYS329 |
| E | HOH203 |
| E | HOH204 |
| G | LEU187 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR CHAIN F OF CK2BETA-DERIVED CYCLIC PEPTIDE |
| Chain | Residue |
| C | TYR39 |
| C | GLN40 |
| C | LEU41 |
| C | GLU52 |
| C | VAL101 |
| C | ASP103 |
| C | THR108 |
| C | GLN36 |
| site_id | BC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR CHAIN G OF CK2BETA-DERIVED CYCLIC PEPTIDE |
| Chain | Residue |
| B | VAL42 |
| B | ARG43 |
| B | LYS44 |
| B | PHE54 |
| C | ARG280 |
| C | GLU282 |
| C | PRO295 |
| C | ASP299 |
| C | PRO322 |
| E | ILE192 |
| G | HOH201 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
| Chain | Residue | Details |
| A | LEU45-LYS68 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 855 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 27 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
