Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4I7N

T4 Lysozyme L99A/M102H with 1-phenyl-2-propyn-1-ol bound

Functional Information from GO Data
ChainGOidnamespacecontents
A0003796molecular_functionlysozyme activity
A0009253biological_processpeptidoglycan catabolic process
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
A0016998biological_processcell wall macromolecule catabolic process
A0030430cellular_componenthost cell cytoplasm
A0031640biological_processkilling of cells of another organism
A0042742biological_processdefense response to bacterium
A0044659biological_processviral release from host cell by cytolysis
B0003796molecular_functionlysozyme activity
B0009253biological_processpeptidoglycan catabolic process
B0016798molecular_functionhydrolase activity, acting on glycosyl bonds
B0016998biological_processcell wall macromolecule catabolic process
B0030430cellular_componenthost cell cytoplasm
B0031640biological_processkilling of cells of another organism
B0042742biological_processdefense response to bacterium
B0044659biological_processviral release from host cell by cytolysis
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE BME A 201
ChainResidue
AILE3
AALA93
ACYS97
AHOH433

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE 1DJ A 202
ChainResidue
ALEU118
APHE153
ALEU84
AALA99
AHIS102
AVAL111
AVAL117

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 203
ChainResidue
AARG14
ALEU15
ALYS16
AHOH335

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 204
ChainResidue
AARG76
AARG80
AHOH428
BLYS135

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 205
ChainResidue
AARG119
AARG125
BLYS48

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 206
ChainResidue
APHE4
AGLU5
AARG8
AILE29
BGLY51
BHOH357

site_idAC7
Number of Residues10
DetailsBINDING SITE FOR RESIDUE BME A 207
ChainResidue
APHE-3
AMET1
AILE9
ATYR161
ALYS162
AASN163
ALEU164
AHOH304
AHOH313
BHOH335

site_idAC8
Number of Residues2
DetailsBINDING SITE FOR RESIDUE BME A 208
ChainResidue
ATHR151
BTHR109

site_idAC9
Number of Residues7
DetailsBINDING SITE FOR RESIDUE HED A 209
ChainResidue
ATHR109
AGLY110
AGLY113
BALA130
BTHR151
BARG154
BHOH346

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ACT B 201
ChainResidue
ALYS135
BARG76
BARG80
BSO4205
BHOH393

site_idBC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE BME B 202
ChainResidue
BILE3
BCYS97

site_idBC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE 1DJ B 203
ChainResidue
BLEU84
BALA99
BHIS102
BVAL111
BPHE153

site_idBC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 B 204
ChainResidue
BARG119
BARG125

site_idBC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 205
ChainResidue
BARG76
BARG80
BACT201
BHOH364

site_idBC6
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ACT B 206
ChainResidue
BLEU15
BLYS16
BHOH396

site_idBC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE BME B 207
ChainResidue
BGLY30
BHIS31
BLEU32
BPHE104
BHOH422
BHOH427

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098
ChainResidueDetails
BGLU11
AGLU11

site_idSWS_FT_FI2
Number of Residues2
DetailsACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098
ChainResidueDetails
BASP20
AASP20

site_idSWS_FT_FI3
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:8266098
ChainResidueDetails
ALEU32
APHE104
BLEU32
BPHE104

site_idSWS_FT_FI4
Number of Residues4
DetailsBINDING: BINDING => ECO:0000303|PubMed:7831309
ChainResidueDetails
AVAL117
AASN132
BVAL117
BASN132

Catalytic Information from CSA
site_idMCSA1
Number of Residues2
DetailsM-CSA 921
ChainResidueDetails
AGLU11proton shuttle (general acid/base)
AASP20covalent catalysis

site_idMCSA2
Number of Residues2
DetailsM-CSA 921
ChainResidueDetails
BGLU11proton shuttle (general acid/base)
BASP20covalent catalysis

219869

PDB entries from 2024-05-15

PDB statisticsPDBj update infoContact PDBjnumon