Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001907 | biological_process | symbiont-mediated killing of host cell |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0031012 | cellular_component | extracellular matrix |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 501 |
| Chain | Residue |
| A | ASP168 |
| A | HOH1040 |
| A | HIS229 |
| A | TYR230 |
| A | ALA231 |
| A | ALA232 |
| A | LYS278 |
| A | ILE280 |
| A | HOH913 |
| A | HOH971 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 502 |
| Chain | Residue |
| A | THR4 |
| A | ASP7 |
| A | TYR130 |
| A | ASN157 |
| A | SER405 |
| A | LYS409 |
| A | HOH874 |
| A | HOH924 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 503 |
| Chain | Residue |
| A | TRP46 |
| A | ASN47 |
| A | VAL56 |
| A | LYS57 |
| A | ASN114 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 504 |
| Chain | Residue |
| A | HIS16 |
| A | ARG18 |
| A | LYS308 |
| A | SER309 |
| A | HOH656 |
| A | HOH947 |
| A | HOH999 |
| A | HOH1096 |
| A | HOH1097 |
| A | HOH1163 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 505 |
| Chain | Residue |
| A | ASN101 |
| A | ALA248 |
| A | ASN249 |
| A | LEU250 |
| A | SER251 |
| A | ASN275 |
| A | HOH715 |
| A | HOH910 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HEX A 506 |
| Chain | Residue |
| A | PRO197 |
| A | TYR216 |
| A | TRP217 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HEX A 507 |
| Chain | Residue |
| A | TYR135 |
| A | ALA136 |
| A | PHE137 |
| A | OCT508 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OCT A 508 |
| Chain | Residue |
| A | PHE137 |
| A | TRP143 |
| A | HEX507 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OCT A 509 |
| Chain | Residue |
| A | GLN34 |
| A | LEU37 |
| A | PHE38 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 510 |
| Chain | Residue |
| A | HIS176 |
| A | HIS180 |
| A | HIS186 |
| A | TYR216 |
| A | HOH1024 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 511 |
| Chain | Residue |
| A | ARG253 |
| A | GLY255 |
| A | THR257 |
| A | ASP285 |
| A | GLY287 |
| A | ASP290 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 512 |
| Chain | Residue |
| A | GLY288 |
| A | ASP290 |
| A | THR327 |
| A | GLU329 |
| A | HOH1051 |
| A | HOH1053 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 513 |
| Chain | Residue |
| A | GLY334 |
| A | GLY336 |
| A | ASP338 |
| A | GLY351 |
| A | ALA353 |
| A | ASP356 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 514 |
| Chain | Residue |
| A | ASN343 |
| A | ALA345 |
| A | ASN347 |
| A | GLY360 |
| A | GLY362 |
| A | ASP365 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 515 |
| Chain | Residue |
| A | GLY352 |
| A | GLY354 |
| A | ASP356 |
| A | GLY369 |
| A | ALA371 |
| A | ASP374 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 516 |
| Chain | Residue |
| A | GLY370 |
| A | GLY372 |
| A | ASP374 |
| A | ASP400 |
| A | HOH1076 |
| A | HOH1134 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 517 |
| Chain | Residue |
| A | ASP383 |
| A | ASP390 |
| A | HOH1071 |
| A | GLY361 |
| A | GLY362 |
| A | GLY363 |
| A | ASP365 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TFTHEIGHAL |
| Chain | Residue | Details |
| A | THR173-LEU182 | |
| site_id | PS00330 |
| Number of Residues | 19 |
| Details | HEMOLYSIN_CALCIUM Hemolysin-type calcium-binding region signature. DvLfgggGaDeLwGGagkD |
| Chain | Residue | Details |
| A | ASP356-ASP374 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 17 |
| Details | Repeat: {"description":"Hemolysin-type calcium-binding 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Repeat: {"description":"Hemolysin-type calcium-binding 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 37 |
| Details | Binding site: {} |
