Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 501 |
| Chain | Residue |
| A | GLU316 |
| A | TRP331 |
| A | ASP451 |
| A | HIS457 |
| A | HIS459 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 502 |
| Chain | Residue |
| A | HOH729 |
| A | ASP192 |
| A | HIS458 |
| A | HIS460 |
| A | HOH628 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 503 |
| Chain | Residue |
| A | GLU78 |
| A | HIS110 |
| A | HIS150 |
| A | HOH785 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 0ZA A 504 |
| Chain | Residue |
| A | GLY72 |
| A | GLN73 |
| A | GLY74 |
| A | LEU91 |
| A | ASP93 |
| A | TYR132 |
| A | GLN134 |
| A | GLY135 |
| A | LYS168 |
| A | GLY291 |
| A | THR292 |
| A | THR293 |
| A | ASN294 |
| A | HOH898 |
| A | HOH912 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE90-VAL101 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP93 | |
| A | ASP289 | |
| Chain | Residue | Details |
| A | LYS126 | |
| A | LYS275 | |
| A | LYS279 | |
| A | LYS285 | |
| A | LYS299 | |
| A | LYS300 | |
| A | LYS307 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN153 | |
| A | ASN172 | |
| A | ASN223 | |
| A | ASN354 | |
