Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4HZC

Crystal structure of Serine acetyltransferase from Brucella abortus strain S19

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006535	biological_process	cysteine biosynthetic process from serine
A	0008652	biological_process	amino acid biosynthetic process
A	0009001	molecular_function	serine O-acetyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0019344	biological_process	cysteine biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006535	biological_process	cysteine biosynthetic process from serine
B	0008652	biological_process	amino acid biosynthetic process
B	0009001	molecular_function	serine O-acetyltransferase activity
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0019344	biological_process	cysteine biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006535	biological_process	cysteine biosynthetic process from serine
C	0008652	biological_process	amino acid biosynthetic process
C	0009001	molecular_function	serine O-acetyltransferase activity
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0019344	biological_process	cysteine biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006535	biological_process	cysteine biosynthetic process from serine
D	0008652	biological_process	amino acid biosynthetic process
D	0009001	molecular_function	serine O-acetyltransferase activity
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0019344	biological_process	cysteine biosynthetic process
D	0046872	molecular_function	metal ion binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006535	biological_process	cysteine biosynthetic process from serine
E	0008652	biological_process	amino acid biosynthetic process
E	0009001	molecular_function	serine O-acetyltransferase activity
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
E	0019344	biological_process	cysteine biosynthetic process
E	0046872	molecular_function	metal ion binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006535	biological_process	cysteine biosynthetic process from serine
F	0008652	biological_process	amino acid biosynthetic process
F	0009001	molecular_function	serine O-acetyltransferase activity
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
F	0019344	biological_process	cysteine biosynthetic process
F	0046872	molecular_function	metal ion binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006535	biological_process	cysteine biosynthetic process from serine
G	0008652	biological_process	amino acid biosynthetic process
G	0009001	molecular_function	serine O-acetyltransferase activity
G	0016740	molecular_function	transferase activity
G	0016746	molecular_function	acyltransferase activity
G	0019344	biological_process	cysteine biosynthetic process
G	0046872	molecular_function	metal ion binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006535	biological_process	cysteine biosynthetic process from serine
H	0008652	biological_process	amino acid biosynthetic process
H	0009001	molecular_function	serine O-acetyltransferase activity
H	0016740	molecular_function	transferase activity
H	0016746	molecular_function	acyltransferase activity
H	0019344	biological_process	cysteine biosynthetic process
H	0046872	molecular_function	metal ion binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006535	biological_process	cysteine biosynthetic process from serine
I	0008652	biological_process	amino acid biosynthetic process
I	0009001	molecular_function	serine O-acetyltransferase activity
I	0016740	molecular_function	transferase activity
I	0016746	molecular_function	acyltransferase activity
I	0019344	biological_process	cysteine biosynthetic process
I	0046872	molecular_function	metal ion binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006535	biological_process	cysteine biosynthetic process from serine
J	0008652	biological_process	amino acid biosynthetic process
J	0009001	molecular_function	serine O-acetyltransferase activity
J	0016740	molecular_function	transferase activity
J	0016746	molecular_function	acyltransferase activity
J	0019344	biological_process	cysteine biosynthetic process
J	0046872	molecular_function	metal ion binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006535	biological_process	cysteine biosynthetic process from serine
K	0008652	biological_process	amino acid biosynthetic process
K	0009001	molecular_function	serine O-acetyltransferase activity
K	0016740	molecular_function	transferase activity
K	0016746	molecular_function	acyltransferase activity
K	0019344	biological_process	cysteine biosynthetic process
K	0046872	molecular_function	metal ion binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006535	biological_process	cysteine biosynthetic process from serine
L	0008652	biological_process	amino acid biosynthetic process
L	0009001	molecular_function	serine O-acetyltransferase activity
L	0016740	molecular_function	transferase activity
L	0016746	molecular_function	acyltransferase activity
L	0019344	biological_process	cysteine biosynthetic process
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TRS A 301

Chain	Residue
A	GLU61
B	HOH304
A	ASP71
A	ARG74
A	HOH513
A	HOH515
B	GLU61
B	ALA70
B	ASP71
B	ARG74

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 302

Chain	Residue
A	TYR105
A	LEU115
A	HOH447
A	HOH523
F	GLN143
F	ASP153

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 303

Chain	Residue
A	GLU61
B	HOH303
F	PRO66
F	ASP67

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 301

Chain	Residue
C	SER69
C	TRS302
C	HOH444
C	HOH501
C	HOH517
D	PRO66

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE TRS C 302

Chain	Residue
C	GLU61
C	ASP71
C	ARG74
C	MG301
C	HOH444
F	GLU61
F	ALA70
F	ASP71
F	ARG74

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 301

Chain	Residue
D	GLU61
D	TRS302

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TRS D 302

Chain	Residue
D	GLU61
D	ALA70
D	ASP71
D	ARG74
D	MG301
D	HOH508
E	GLU61
E	ALA70
E	ASP71
E	ARG74
E	HOH371

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 301

Chain	Residue
F	HIS57
F	ALA60
F	GLU61
F	ARG74

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL G 301

Chain	Residue
G	HIS57
G	ALA60
G	GLU61
G	ARG74
K	TRS302

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG G 302

Chain	Residue
G	SER69
G	ASP71
G	HOH426
K	TRS302
K	HOH442
L	PRO66
L	HOH348

site_id	BC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE TRS I 301

Chain	Residue
I	GLU61
I	ALA70
I	ASP71
J	GLU61
J	ALA70
J	ASP71
J	ARG74
J	MG303

site_id	BC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 15P J 301

Chain	Residue
J	HIS65
J	PRO66
J	SER69
J	HOH457
K	PRO66
K	SER69
K	MG301
K	TRS302
K	HOH461

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG J 302

Chain	Residue
H	HOH388
I	HOH441
J	HIS57
J	GLU61

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG J 303

Chain	Residue
I	TRS301
J	HIS57
J	ALA60
J	GLU61
J	ARG74

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG K 301

Chain	Residue
I	HOH459
J	SER69
J	ASP71
J	15P301
K	PRO66

site_id	BC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE TRS K 302

Chain	Residue
G	CL301
G	MG302
J	15P301
K	GLU61
K	ALA70
K	ASP71
K	ARG74
G	GLU61
G	ALA70
G	ASP71
G	ARG74

Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IGagAkIlgnIqVGqcSkIAagSvVlksV

Chain	Residue	Details
A	ILE212-VAL240

site_id	PS01159
Number of Residues	25
Details	WW_DOMAIN_1 WW/rsp5/WWP domain signature. Wshvlrvdiqa.VYdrdpay.SRFMDP

Chain	Residue	Details
A	TRP87-PRO111

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)