4HVK
Crystal structure and functional studies of an unusual L-cysteine desulfurase from Archaeoglobus fulgidus.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016226 | biological_process | iron-sulfur cluster assembly |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0031071 | molecular_function | cysteine desulfurase activity |
| A | 0044571 | biological_process | [2Fe-2S] cluster assembly |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA A 401 |
| Chain | Residue |
| A | PG4405 |
| A | HOH814 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | GLY121 |
| A | LYS122 |
| A | TYR123 |
| A | GLY124 |
| A | GLU125 |
| A | HOH829 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | HIS98 |
| A | ASP173 |
| A | THR175 |
| A | ASN73 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE PMP A 404 |
| Chain | Residue |
| A | THR7 |
| A | ALA69 |
| A | THR70 |
| A | ASN73 |
| A | HIS98 |
| A | SER100 |
| A | ASN149 |
| A | ASP173 |
| A | THR175 |
| A | SER234 |
| A | HOH509 |
| A | HOH556 |
| A | HOH585 |
| A | HOH593 |
| A | HOH665 |
| A | HOH709 |
| A | HOH790 |
| A | HOH825 |
| A | HOH826 |
| A | HOH827 |
| A | HOH867 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 405 |
| Chain | Residue |
| A | TYR123 |
| A | GLY166 |
| A | LYS213 |
| A | PRO284 |
| A | CA401 |
| A | HOH764 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PG4 A 406 |
| Chain | Residue |
| A | LEU55 |
| A | VAL178 |
| A | GLY179 |
| A | ILE181 |
| A | GLU182 |
| A | VAL183 |
| A | TRP254 |
| A | HOH870 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PG4 A 407 |
| Chain | Residue |
| A | GLU26 |
| A | LYS40 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 A 408 |
| Chain | Residue |
| A | ASN103 |
| A | LYS110 |
| A | LEU222 |
| A | PG4410 |
| A | HOH828 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PG4 A 409 |
| Chain | Residue |
| A | ILE102 |
| A | LYS106 |
| A | TYR117 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG4 A 410 |
| Chain | Residue |
| A | LYS110 |
| A | PG4408 |
| A | HOH775 |
| A | HOH828 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PG4 A 411 |
| Chain | Residue |
| A | ARG295 |
| A | GLU341 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PG4 A 412 |
| Chain | Residue |
| A | TYR298 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG4 A 413 |
| Chain | Residue |
| A | ARG15 |
| A | ALA19 |
| A | LYS245 |
| A | GLU248 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG4 A 414 |
| Chain | Residue |
| A | THR25 |
| A | TYR353 |
| A | HOH730 |
| A | HOH864 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00331","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22511353","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23160436","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00331","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22511353","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
