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4HUF

Structure of 5-chlorouracil modified A:U base pair

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0004523molecular_functionRNA-DNA hybrid ribonuclease activity
B0003676molecular_functionnucleic acid binding
B0004523molecular_functionRNA-DNA hybrid ribonuclease activity
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE GOL A 201
ChainResidue
AGLY76
AASN77
APRO78
AHOH348
AHOH356
AHOH419
BTHR176
BPRO177
BILE178

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG A 202
ChainResidue
AASP71
AGLU109
AASN132
AHOH338
AHOH346
AHOH384
AHOH394

site_idAC3
Number of Residues11
DetailsBINDING SITE FOR RESIDUE GOL C 101
ChainResidue
ATHR135
CDG2
CHOH201
CHOH204
CHOH205
CHOH206
CHOH219
DDG22
DDC23
DDG24
DHOH107

site_idAC4
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG E 101
ChainResidue
EDG2
EHOH205
EHOH212
EHOH213
EHOH216
EHOH217
EHOH218

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO F 101
ChainResidue
ALYS143
ATHR173
ATYR174
FDG24
FHOH203

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO F 102
ChainResidue
ALYS141
EDG2
EDC3
EHOH205
FDG22
FHOH204

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:15989951
ChainResidueDetails
AASP71
AGLU109
AASN132
AASP192
BASP71
BGLU109
BASN132
BASP192

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PDB entries from 2024-11-06

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