4HUE

Structure of 5-chlorouracil modified G:U base pair

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
B	0003676	molecular_function	nucleic acid binding
B	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 201

Chain	Residue
A	GLY76
A	ASN77
A	PRO78
A	HOH357
A	HOH407
A	HOH417
B	THR176
B	PRO177
B	ILE178

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 202

Chain	Residue
A	LYS143
A	THR173
A	TYR174
A	HOH423
F	DC23
F	DG24
F	HOH103
F	HOH107

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 203

Chain	Residue
A	ASP71
A	GLU109
A	ASN132
A	HOH340
A	HOH349
A	HOH383
A	HOH445

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site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL D 101

Chain	Residue
A	THR135
C	DG2
C	HOH127
D	DG22
D	DC23
D	DG24
D	HOH201
D	HOH203
D	HOH204
D	HOH208
D	HOH220

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site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GOL E 101

Chain	Residue
A	LYS141
A	ASP142
E	DG2
E	DC3
E	MG102
E	HOH215
E	HOH216
E	HOH217
E	HOH219
F	UCL21
F	DG22
F	HOH119

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site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG E 102

Chain	Residue
E	DG2
E	GOL101
E	HOH210
E	HOH211
E	HOH213
E	HOH214
E	HOH216

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:15989951

Chain	Residue	Details
A	ASP71
A	GLU109
A	ASN132
A	ASP192
B	ASP71
B	GLU109
B	ASN132
B	ASP192

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