4HO6

Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-glucose and UTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
A	0009058	biological_process	biosynthetic process
A	0016779	molecular_function	nucleotidyltransferase activity
A	0045226	biological_process	extracellular polysaccharide biosynthetic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE UPG A 300

Chain	Residue
A	LEU6
A	PHE143
A	GLY144
A	GLU159
A	LYS160
A	VAL170
A	ARG192
A	HOH402
A	HOH403
A	HOH408
A	HOH411
A	GLY8
A	HOH413
A	HOH526
A	GLY9
A	GLN80
A	PRO83
A	ASP84
A	GLY85
A	LEU106
A	ASP108

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site_id	AC2
Number of Residues	24
Details	BINDING SITE FOR RESIDUE UTP A 301

Chain	Residue
A	LEU43
A	TYR112
A	GLY113
A	HIS114
A	GLY115
A	PHE116
A	THR117
A	GLY216
A	ARG217
A	GLY218
A	VAL248
A	ALA249
A	GLU253
A	ILE254
A	ARG257
A	HOH406
A	HOH418
A	HOH427
A	HOH432
A	HOH466
A	HOH472
A	HOH516
A	HOH549
A	HOH576

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 302

Chain	Residue
A	GLY11
A	THR12
A	ARG13

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 303

Chain	Residue
A	GLY66
A	GLY67
A	SER69
A	TYR77
A	ALA78
A	VAL79
A	HOH473
A	HOH512
A	HOH563

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