4HO3

Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine triphosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
A	0009058	biological_process	biosynthetic process
A	0016779	molecular_function	nucleotidyltransferase activity
A	0045226	biological_process	extracellular polysaccharide biosynthetic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE TTP A 300

Chain	Residue
A	LEU6
A	PRO83
A	ASP84
A	GLY85
A	LEU86
A	GLY107
A	ASP108
A	GLU194
A	HOH495
A	HOH510
A	HOH599
A	GLY8
A	GLY9
A	SER10
A	GLY11
A	THR12
A	ARG13
A	GLN24
A	GLN80

---

site_id	AC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE TTP A 301

Chain	Residue
A	LEU43
A	TYR112
A	GLY113
A	HIS114
A	GLY115
A	PHE116
A	THR117
A	GLY216
A	ARG217
A	GLY218
A	VAL248
A	ALA249
A	GLU253
A	ILE254
A	ARG257
A	HOH406
A	HOH407
A	HOH409
A	HOH455
A	HOH500
A	HOH587

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 302

Chain	Residue
A	GLY66
A	GLY67
A	GLY68
A	SER69
A	GLU70
A	HOH421
A	HOH479
A	HOH493
A	HOH505

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 303

Chain	Residue
A	LYS153
A	HIS211
A	LYS268
A	HOH502
A	HOH513
A	HOH553

---