Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4HNZ

Crystal structure of eukaryotic HslV from Trypanosoma brucei

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004298	molecular_function	threonine-type endopeptidase activity
A	0005839	cellular_component	proteasome core complex
A	0006508	biological_process	proteolysis
A	0009376	cellular_component	HslUV protease complex
A	0051603	biological_process	proteolysis involved in protein catabolic process
B	0004298	molecular_function	threonine-type endopeptidase activity
B	0005839	cellular_component	proteasome core complex
B	0006508	biological_process	proteolysis
B	0009376	cellular_component	HslUV protease complex
B	0051603	biological_process	proteolysis involved in protein catabolic process
C	0004298	molecular_function	threonine-type endopeptidase activity
C	0005839	cellular_component	proteasome core complex
C	0006508	biological_process	proteolysis
C	0009376	cellular_component	HslUV protease complex
C	0051603	biological_process	proteolysis involved in protein catabolic process
D	0004298	molecular_function	threonine-type endopeptidase activity
D	0005839	cellular_component	proteasome core complex
D	0006508	biological_process	proteolysis
D	0009376	cellular_component	HslUV protease complex
D	0051603	biological_process	proteolysis involved in protein catabolic process
E	0004298	molecular_function	threonine-type endopeptidase activity
E	0005839	cellular_component	proteasome core complex
E	0006508	biological_process	proteolysis
E	0009376	cellular_component	HslUV protease complex
E	0051603	biological_process	proteolysis involved in protein catabolic process
F	0004298	molecular_function	threonine-type endopeptidase activity
F	0005839	cellular_component	proteasome core complex
F	0006508	biological_process	proteolysis
F	0009376	cellular_component	HslUV protease complex
F	0051603	biological_process	proteolysis involved in protein catabolic process
G	0004298	molecular_function	threonine-type endopeptidase activity
G	0005839	cellular_component	proteasome core complex
G	0006508	biological_process	proteolysis
G	0009376	cellular_component	HslUV protease complex
G	0051603	biological_process	proteolysis involved in protein catabolic process
H	0004298	molecular_function	threonine-type endopeptidase activity
H	0005839	cellular_component	proteasome core complex
H	0006508	biological_process	proteolysis
H	0009376	cellular_component	HslUV protease complex
H	0051603	biological_process	proteolysis involved in protein catabolic process
I	0004298	molecular_function	threonine-type endopeptidase activity
I	0005839	cellular_component	proteasome core complex
I	0006508	biological_process	proteolysis
I	0009376	cellular_component	HslUV protease complex
I	0051603	biological_process	proteolysis involved in protein catabolic process
J	0004298	molecular_function	threonine-type endopeptidase activity
J	0005839	cellular_component	proteasome core complex
J	0006508	biological_process	proteolysis
J	0009376	cellular_component	HslUV protease complex
J	0051603	biological_process	proteolysis involved in protein catabolic process
K	0004298	molecular_function	threonine-type endopeptidase activity
K	0005839	cellular_component	proteasome core complex
K	0006508	biological_process	proteolysis
K	0009376	cellular_component	HslUV protease complex
K	0051603	biological_process	proteolysis involved in protein catabolic process
L	0004298	molecular_function	threonine-type endopeptidase activity
L	0005839	cellular_component	proteasome core complex
L	0006508	biological_process	proteolysis
L	0009376	cellular_component	HslUV protease complex
L	0051603	biological_process	proteolysis involved in protein catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 200

Chain	Residue
A	THR157
A	ASP160
A	SER163
A	HOH342

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 200

Chain	Residue
B	THR157
B	ASP160
B	SER163
B	HOH305

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 200

Chain	Residue
C	ASP160
C	SER163
C	HOH304
C	THR157

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 200

Chain	Residue
D	THR157
D	ASP160
D	SER163

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 200

Chain	Residue
E	THR157
E	ASP160
E	SER163
E	HOH331

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 200

Chain	Residue
F	THR157
F	ASP160
F	SER163
F	HOH330
F	HOH353

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 200

Chain	Residue
G	THR157
G	ASP160
G	SER163
G	HOH310
G	HOH358
G	HOH360

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG H 200

Chain	Residue
H	THR157
H	ASP160
H	SER163

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG I 200

Chain	Residue
I	THR157
I	ASP160
I	SER163

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG J 200

Chain	Residue
J	THR157
J	ASP160
J	SER163
J	HOH329
J	HOH339

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG K 200

Chain	Residue
K	THR157
K	ASP160
K	SER163
K	HOH323

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG L 200

Chain	Residue
L	THR157
L	ASP160
L	SER163
L	HOH309
L	HOH324
L	HOH335

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
A	THR1
J	THR1
K	THR1
L	THR1
B	THR1
C	THR1
D	THR1
E	THR1
F	THR1
G	THR1
H	THR1
I	THR1

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)