4HKF
Crystal structure of Danio rerio MEC-17 catalytic domain in complex with acetyl-CoA
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE ACO A 201 |
| Chain | Residue |
| A | GLN53 |
| A | HIS127 |
| A | GLY128 |
| A | TYR129 |
| A | GLY130 |
| A | SER131 |
| A | ASP151 |
| A | ARG152 |
| A | PRO153 |
| A | SER154 |
| A | LYS156 |
| A | LYS96 |
| A | PHE157 |
| A | SER159 |
| A | PHE160 |
| A | LYS163 |
| A | SO4202 |
| A | HOH301 |
| A | HOH302 |
| A | HOH331 |
| A | HOH366 |
| A | HOH380 |
| A | VAL115 |
| A | HOH391 |
| A | HOH406 |
| A | HOH419 |
| A | HOH432 |
| A | HOH467 |
| A | HOH481 |
| A | ASP117 |
| A | PHE118 |
| A | TYR119 |
| A | VAL120 |
| A | GLN125 |
| A | ARG126 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | ARG69 |
| A | ARG126 |
| A | LYS163 |
| A | ACO201 |
| A | HOH536 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | ASP6 |
| A | GLY82 |
| A | GLY83 |
| A | HOH519 |
| A | HOH542 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 204 |
| Chain | Residue |
| A | PRO4 |
| A | ASP6 |
| A | ARG84 |
| A | GLN103 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03130","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23105108","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23128673","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Crucial for catalytic activity","evidences":[{"source":"HAMAP-Rule","id":"MF_03130","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23128673","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
