Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4HJH

Iodide SAD phased crystal structure of a phosphoglucomutase from Brucella melitensis complexed with glucose-6-phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005975	biological_process	carbohydrate metabolic process
A	0016868	molecular_function	intramolecular phosphotransferase activity
B	0000287	molecular_function	magnesium ion binding
B	0005975	biological_process	carbohydrate metabolic process
B	0016868	molecular_function	intramolecular phosphotransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 501

Chain	Residue
A	ASN21

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 502

Chain	Residue
A	THR196

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 503

Chain	Residue
A	ARG176

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 504

Chain	Residue
A	ARG206
A	HOH644

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 505

Chain	Residue
A	ARG297
A	HOH846

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 508

Chain	Residue
A	HOH828

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 511

Chain	Residue
A	SER406
A	LYS47

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 513

Chain	Residue
A	THR454

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 514

Chain	Residue
A	HOH924

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 515

Chain	Residue
A	LYS7
A	ALA441
A	PRO442

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 516

Chain	Residue
A	GLY15
A	ARG110
A	ASN440

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 518

Chain	Residue
A	ARG118

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 520

Chain	Residue
A	GLU361

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 521

Chain	Residue
A	HOH845

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 522

Chain	Residue
A	ALA203

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 526

Chain	Residue
A	ARG176

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 527

Chain	Residue
A	VAL417

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 529

Chain	Residue
A	THR392

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 531

Chain	Residue
A	THR195
A	HOH870

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IOD A 532

Chain	Residue
A	GLN157
A	ALA410
A	GLY411
A	HOH636

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IOD A 534

Chain	Residue
A	ARG259
A	HOH674
A	HOH721
A	HOH883

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 536

Chain	Residue
A	LEU294

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 539

Chain	Residue
A	HOH931
A	HOH938

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 541

Chain	Residue
A	HOH907

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 542

Chain	Residue
A	HOH918

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 543

Chain	Residue
A	GLU399
A	ARG404

site_id	CC9
Number of Residues	18
Details	BINDING SITE FOR RESIDUE G6Q A 544

Chain	Residue
A	THR10
A	SER11
A	ARG14
A	SEP104
A	HIS105
A	GLU216
A	ARG247
A	VAL298
A	GLY299
A	SER300
A	GLU322
A	ASN324
A	ARG436
A	SER438
A	GLY439
A	ASN440
A	ARG445
A	HOH695

site_id	DC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 545

Chain	Residue
A	VAL81
A	ARG187
A	ASP188
A	ARG206
A	HOH810
A	HOH834

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 546

Chain	Residue
A	ARG335
A	ALA357
A	HIS360
A	HOH865

site_id	DC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 547

Chain	Residue
A	PHE290
A	HOH740
A	HOH769
A	HOH889
A	HOH892

site_id	DC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 548

Chain	Residue
A	VAL280
A	THR281
A	LYS424
A	HIS434
A	TYR447
A	HOH662
A	HOH714

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 549

Chain	Residue
A	GLU334
A	ARG335
A	ASN336
A	GLY337

site_id	DC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 550

Chain	Residue
A	PRO409
A	ASP412
A	PHE427
A	ASN431
A	LEU459
A	LEU462
A	HOH694
A	HOH732

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 551

Chain	Residue
A	LEU464
A	GLU465
A	ARG468

site_id	DC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 552

Chain	Residue
A	ASP244
A	ASP246
A	SEP104
A	ASP242

site_id	DC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 501

Chain	Residue
B	ASN21

site_id	EC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 502

Chain	Residue
B	ARG118

site_id	EC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 503

Chain	Residue
B	THR196
B	HOH686

site_id	EC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 504

Chain	Residue
B	HOH693

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 506

Chain	Residue
B	ARG176

site_id	EC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 507

Chain	Residue
B	ARG206

site_id	EC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 508

Chain	Residue
B	ALA203

site_id	EC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 509

Chain	Residue
B	HOH778

site_id	EC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 511

Chain	Residue
B	ARG297

site_id	EC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 512

Chain	Residue
B	LEU294

site_id	FC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 513

Chain	Residue
B	HOH819

site_id	FC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 516

Chain	Residue
B	HOH720

site_id	FC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 518

Chain	Residue
B	THR454

site_id	FC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 519

Chain	Residue
B	TYR134

site_id	FC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 521

Chain	Residue
B	ALA441
B	PRO442

site_id	FC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 522

Chain	Residue
B	PRO56
B	PHE210

site_id	FC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 523

Chain	Residue
B	IOD524

site_id	FC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 524

Chain	Residue
B	GLY22
B	IOD523

site_id	FC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 525

Chain	Residue
B	THR195

site_id	GC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 526

Chain	Residue
B	ARG206

site_id	GC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 527

Chain	Residue
B	GLU361
B	HOH654

site_id	GC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 529

Chain	Residue
B	SER131

site_id	GC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD B 531

Chain	Residue
B	THR152
B	ASP153
B	ALA154

site_id	GC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 532

Chain	Residue
B	THR392

site_id	GC6
Number of Residues	20
Details	BINDING SITE FOR RESIDUE G6Q B 533

Chain	Residue
B	THR10
B	SER11
B	ARG14
B	SEP104
B	HIS105
B	GLU216
B	ARG247
B	VAL298
B	GLY299
B	SER300
B	GLU322
B	ASN324
B	ARG346
B	ARG436
B	SER438
B	GLY439
B	ASN440
B	ARG445
B	HOH714
B	HOH738

site_id	GC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO B 534

Chain	Residue
B	HOH707

site_id	GC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 535

Chain	Residue
B	SEP104
B	ASP242
B	ASP244
B	ASP246

Functional Information from PROSITE/UniProt

site_id	PS00710
Number of Residues	10
Details	PGM_PMM Phosphoglucomutase and phosphomannomutase phosphoserine signature. SImVTGSHIP

Chain	Residue	Details
A	SER98-PRO107

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)