4HG7

Crystal Structure of an MDM2/Nutlin-3a complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NUT A 201

Chain	Residue
A	PRO32
A	HIS96
A	SO4202
A	HOH307
A	HOH327
A	HOH338
A	LEU54
A	LEU57
A	GLY58
A	ILE61
A	MET62
A	GLN72
A	HIS73
A	VAL93

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 202

Chain	Residue
A	LYS31
A	GLN71
A	GLN72
A	HIS73
A	NUT201
A	HOH320
A	HOH324
A	HOH331
A	HOH347

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