Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE G52 A 401 |
| Chain | Residue |
| A | ARG8 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | HOH1001 |
| A | HOH1002 |
| A | HOH1092 |
| A | HOH1093 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| A | ASP25 |
| B | ASP129 |
| B | ASN130 |
| B | VAL132 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | PRO181 |
| B | VAL182 |
| B | HOH307 |
| B | HOH383 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASN30 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 402 |
| Chain | Residue |
| A | ASP60 |
| A | HOH1003 |
| A | HOH1004 |
| A | HOH1005 |
| A | HOH1006 |
| A | HOH1007 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 403 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH1074 |
| B | ARG141 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 201 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADNTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE199 | |
