4H73
Thermostable aldehyde dehydrogenase from Pyrobaculum sp. complexed with NADP+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NDP A 501 |
| Chain | Residue |
| A | ILE151 |
| A | GLY215 |
| A | PHE229 |
| A | THR230 |
| A | GLY231 |
| A | GLU232 |
| A | THR235 |
| A | ILE239 |
| A | HOH722 |
| A | THR152 |
| A | PRO153 |
| A | TRP154 |
| A | LYS178 |
| A | PRO179 |
| A | ALA180 |
| A | SER181 |
| A | GLY211 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 502 |
| Chain | Residue |
| A | HIS467 |
| A | HOH763 |
| B | HIS467 |
| B | HOH704 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NDP B 500 |
| Chain | Residue |
| B | ILE151 |
| B | THR152 |
| B | PRO153 |
| B | TRP154 |
| B | LYS178 |
| B | PRO179 |
| B | SER181 |
| B | GLY209 |
| B | GLY211 |
| B | GLY215 |
| B | GLU216 |
| B | PHE229 |
| B | THR230 |
| B | GLY231 |
| B | GLU232 |
| B | THR235 |
| B | ILE239 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE NDP C 501 |
| Chain | Residue |
| C | ILE151 |
| C | THR152 |
| C | PRO153 |
| C | TRP154 |
| C | LYS178 |
| C | PRO179 |
| C | ALA180 |
| C | SER181 |
| C | GLY209 |
| C | PRO210 |
| C | GLY211 |
| C | GLY215 |
| C | GLU216 |
| C | PHE229 |
| C | GLY231 |
| C | GLU232 |
| C | THR235 |
| C | HOH719 |
| C | HOH743 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI C 502 |
| Chain | Residue |
| C | HIS467 |
| C | HOH728 |
| D | HIS467 |
| D | HOH717 |
| D | HOH771 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NDP D 500 |
| Chain | Residue |
| D | ILE151 |
| D | THR152 |
| D | PRO153 |
| D | TRP154 |
| D | LYS178 |
| D | PRO179 |
| D | ALA180 |
| D | SER181 |
| D | GLY211 |
| D | GLY215 |
| D | PHE229 |
| D | THR230 |
| D | GLY231 |
| D | GLU232 |
| D | THR235 |
| D | ILE239 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NDP E 501 |
| Chain | Residue |
| E | ILE151 |
| E | THR152 |
| E | PRO153 |
| E | TRP154 |
| E | LYS178 |
| E | ALA180 |
| E | SER181 |
| E | PRO210 |
| E | GLY211 |
| E | GLY215 |
| E | PHE229 |
| E | THR230 |
| E | GLY231 |
| E | GLU232 |
| E | THR235 |
| E | HOH719 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI E 502 |
| Chain | Residue |
| E | HIS467 |
| F | HIS467 |
| F | HOH705 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NDP F 500 |
| Chain | Residue |
| F | PRO153 |
| F | TRP154 |
| F | LYS178 |
| F | PRO179 |
| F | ALA180 |
| F | SER181 |
| F | PRO210 |
| F | GLY211 |
| F | GLY215 |
| F | GLU216 |
| F | PHE229 |
| F | THR230 |
| F | GLY231 |
| F | GLU232 |
| F | THR235 |
| F | HOH762 |
| F | ILE151 |
| F | THR152 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE NDP G 501 |
| Chain | Residue |
| G | ILE151 |
| G | THR152 |
| G | PRO153 |
| G | TRP154 |
| G | LYS178 |
| G | ALA180 |
| G | SER181 |
| G | GLY211 |
| G | GLY215 |
| G | PHE229 |
| G | GLY231 |
| G | GLU232 |
| G | THR235 |
| G | ILE239 |
| G | HOH741 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI G 502 |
| Chain | Residue |
| G | HIS467 |
| H | HIS467 |
| site_id | BC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NDP H 500 |
| Chain | Residue |
| H | ILE151 |
| H | THR152 |
| H | PRO153 |
| H | TRP154 |
| H | LYS178 |
| H | PRO179 |
| H | ALA180 |
| H | SER181 |
| H | PRO210 |
| H | GLY211 |
| H | GLY215 |
| H | PHE229 |
| H | THR230 |
| H | GLY231 |
| H | GLU232 |
| H | THR235 |
| H | HOH717 |
| H | HOH758 |
