4H6K
W116I mutant of OYE1
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE FMN A 401 |
| Chain | Residue |
| A | PRO34 |
| A | GLY324 |
| A | ASN325 |
| A | TYR346 |
| A | GLY347 |
| A | ARG348 |
| A | PHE374 |
| A | TYR375 |
| A | HOH503 |
| A | HOH519 |
| A | HOH528 |
| A | PRO35 |
| A | HOH637 |
| A | LEU36 |
| A | THR37 |
| A | GLY72 |
| A | GLN114 |
| A | HIS191 |
| A | ASN194 |
| A | ARG243 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | ASP83 |
| A | ASN126 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 403 |
| Chain | Residue |
| A | HOH569 |
| A | HOH586 |
| A | HOH649 |
| A | HOH657 |
| A | HOH658 |
| A | HOH768 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 1PE A 404 |
| Chain | Residue |
| A | ASP370 |
| A | HIS380 |
| A | ASP384 |
| A | HOH600 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 1PE A 405 |
| Chain | Residue |
| A | THR58 |
| A | GLN62 |
| A | LYS107 |
| A | HOH574 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"9830020","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11668181","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7881908","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9830019","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11668181","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7881908","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 319 |
| Chain | Residue | Details |
| A | THR37 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS191 | electrostatic stabiliser, hydrogen bond donor |
| A | ASN194 | electrostatic stabiliser, hydrogen bond donor |
| A | TYR196 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN251 | hydrogen bond donor, increase acidity |
