4H3A

Structure of E. coli undecaprenyl diphosphate synthase in complex with BPH-1330

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004659	molecular_function	prenyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008834	molecular_function	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016094	biological_process	polyprenol biosynthetic process
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0036094	molecular_function	small molecule binding
A	0042803	molecular_function	protein homodimerization activity
A	0043164	biological_process	Gram-negative-bacterium-type cell wall biogenesis
A	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
B	0000287	molecular_function	magnesium ion binding
B	0004659	molecular_function	prenyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008834	molecular_function	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
B	0009252	biological_process	peptidoglycan biosynthetic process
B	0016094	biological_process	polyprenol biosynthetic process
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0036094	molecular_function	small molecule binding
B	0042803	molecular_function	protein homodimerization activity
B	0043164	biological_process	Gram-negative-bacterium-type cell wall biogenesis
B	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE 0YY A 301

Chain	Residue
A	ALA47
B	GLN164
B	GLY165
B	ASN166
A	ARG51
A	VAL54
A	SER55
A	LEU93
A	GLU96
A	SER99
A	LEU100
A	HIS103

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 0YY B 301

Chain	Residue
B	ILE38
B	ALA47
B	VAL50
B	ARG51
B	SER55
B	GLU96
B	SER99
B	ARG102
B	HIS103

---

Functional Information from PROSITE/UniProt

site_id	PS01066
Number of Residues	18
Details	UPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. DLVIRTGGehRiSnFLLW

Chain	Residue	Details
A	ASP190-TRP207

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15044730","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15044730","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Site: {"description":"Required for continued chain elongation"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Site: {"description":"Important for determining product length"}

Chain

Residue

Details

---