4H2Z
Crystal structure of human GLTP bound with 12:0 monosulfatide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006869 | biological_process | lipid transport |
| A | 0008289 | molecular_function | lipid binding |
| A | 0017089 | molecular_function | glycolipid transfer activity |
| A | 0035627 | biological_process | ceramide transport |
| A | 0035902 | biological_process | response to immobilization stress |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046317 | biological_process | regulation of glucosylceramide biosynthetic process |
| A | 0046836 | biological_process | glycolipid transport |
| A | 0051861 | molecular_function | glycolipid binding |
| A | 0106254 | molecular_function | lipid sensor activity |
| A | 0120009 | biological_process | intermembrane lipid transfer |
| A | 0120013 | molecular_function | lipid transfer activity |
| A | 1902387 | molecular_function | ceramide 1-phosphate binding |
| A | 1902388 | molecular_function | ceramide 1-phosphate transfer activity |
| A | 1902389 | biological_process | ceramide 1-phosphate transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE EIS A 301 |
| Chain | Residue |
| A | VAL41 |
| A | PHE103 |
| A | LEU136 |
| A | HIS140 |
| A | HIS140 |
| A | PHE148 |
| A | TYR207 |
| A | MYS302 |
| A | HOH418 |
| A | HOH514 |
| A | HOH536 |
| A | PHE42 |
| A | HOH568 |
| A | HOH602 |
| A | ILE45 |
| A | ILE45 |
| A | ASP48 |
| A | ASN52 |
| A | LEU92 |
| A | ALA93 |
| A | TRP96 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MYS A 302 |
| Chain | Residue |
| A | PHE33 |
| A | LEU37 |
| A | PHE103 |
| A | PHE107 |
| A | LEU152 |
| A | PHE183 |
| A | EIS301 |
| A | HOH615 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MYS A 303 |
| Chain | Residue |
| A | LYS87 |
| A | LEU205 |
| A | ASN206 |
| A | TYR207 |
| A | HOH622 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 304 |
| Chain | Residue |
| A | HOH431 |
| A | HOH511 |
| A | HOH544 |
| A | HOH606 |
| A | HOH627 |
| A | HOH650 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Repeat: {"description":"1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Repeat: {"description":"2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Region: {"description":"2 X 12 AA approximate tandem repeats"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15329726","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1SX6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
