4H1T
X-RAY Structure of the Complex VchUPh with Phosphate ion at 1.92A Resolution.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004850 | molecular_function | uridine phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0009164 | biological_process | nucleoside catabolic process |
| A | 0009166 | biological_process | nucleotide catabolic process |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0044206 | biological_process | UMP salvage |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004850 | molecular_function | uridine phosphorylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0009164 | biological_process | nucleoside catabolic process |
| B | 0009166 | biological_process | nucleotide catabolic process |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0044206 | biological_process | UMP salvage |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004850 | molecular_function | uridine phosphorylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0009164 | biological_process | nucleoside catabolic process |
| C | 0009166 | biological_process | nucleotide catabolic process |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0016763 | molecular_function | pentosyltransferase activity |
| C | 0044206 | biological_process | UMP salvage |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004850 | molecular_function | uridine phosphorylase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0009116 | biological_process | nucleoside metabolic process |
| D | 0009164 | biological_process | nucleoside catabolic process |
| D | 0009166 | biological_process | nucleotide catabolic process |
| D | 0016757 | molecular_function | glycosyltransferase activity |
| D | 0016763 | molecular_function | pentosyltransferase activity |
| D | 0044206 | biological_process | UMP salvage |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004850 | molecular_function | uridine phosphorylase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0009116 | biological_process | nucleoside metabolic process |
| E | 0009164 | biological_process | nucleoside catabolic process |
| E | 0009166 | biological_process | nucleotide catabolic process |
| E | 0016757 | molecular_function | glycosyltransferase activity |
| E | 0016763 | molecular_function | pentosyltransferase activity |
| E | 0044206 | biological_process | UMP salvage |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004850 | molecular_function | uridine phosphorylase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0009116 | biological_process | nucleoside metabolic process |
| F | 0009164 | biological_process | nucleoside catabolic process |
| F | 0009166 | biological_process | nucleotide catabolic process |
| F | 0016757 | molecular_function | glycosyltransferase activity |
| F | 0016763 | molecular_function | pentosyltransferase activity |
| F | 0044206 | biological_process | UMP salvage |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0047847 | molecular_function | deoxyuridine phosphorylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 301 |
| Chain | Residue |
| A | GLU48 |
| A | ILE68 |
| A | SER72 |
| B | GLU48 |
| B | ILE68 |
| B | SER72 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 302 |
| Chain | Residue |
| D | TYR52 |
| A | GLU246 |
| A | ARG249 |
| D | GLN31 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 303 |
| Chain | Residue |
| A | ARG177 |
| C | ARG177 |
| E | ARG177 |
| E | SO4303 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 304 |
| Chain | Residue |
| A | EDO311 |
| A | HOH524 |
| C | PHE42 |
| C | TYR52 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 305 |
| Chain | Residue |
| A | GLU35 |
| A | LEU36 |
| A | MET37 |
| A | EDO311 |
| A | PEG320 |
| C | GLN31 |
| C | TYR52 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 306 |
| Chain | Residue |
| A | ARG174 |
| A | VAL175 |
| A | VAL176 |
| A | GLN180 |
| A | HOH464 |
| A | HOH578 |
| C | MET189 |
| C | EDO306 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 307 |
| Chain | Residue |
| A | PRO24 |
| A | GLY25 |
| A | ASP26 |
| A | ARG29 |
| A | EDO308 |
| A | HOH475 |
| A | HOH514 |
| B | ARG47 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 308 |
| Chain | Residue |
| A | ARG90 |
| A | THR93 |
| A | EDO307 |
| A | HOH561 |
| B | ARG47 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 309 |
| Chain | Residue |
| A | GLY104 |
| A | GLY147 |
| A | ARG239 |
| A | HOH448 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 310 |
| Chain | Residue |
| A | ARG114 |
| A | ASP116 |
| A | LEU120 |
| A | MET125 |
| A | ARG178 |
| A | HOH580 |
| F | GLU126 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 311 |
| Chain | Residue |
| A | GLU35 |
| A | MET37 |
| A | PRO40 |
| A | EDO304 |
| A | EDO305 |
| A | HOH420 |
| A | HOH515 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EOH A 312 |
| Chain | Residue |
| A | ARG47 |
| B | ASP26 |
| B | ALA28 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 313 |
| Chain | Residue |
| A | HOH429 |
| A | HOH444 |
| A | HOH508 |
| A | HOH537 |
| F | SO4303 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 314 |
| Chain | Residue |
| A | GLY147 |
| A | HOH430 |
| A | HOH495 |
| D | VAL41 |
| D | ARG53 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 315 |
| Chain | Residue |
| A | LYS184 |
| A | GLU185 |
| A | HOH526 |
| A | HOH581 |
| E | GLN180 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 316 |
| Chain | Residue |
| A | PRO40 |
| A | VAL41 |
| A | PHE42 |
| A | HOH422 |
| E | ASN39 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 317 |
| Chain | Residue |
| A | LYS234 |
| A | ALA238 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 318 |
| Chain | Residue |
| A | ILE219 |
| A | LEU233 |
| A | LYS234 |
| A | GLU237 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EOH A 319 |
| Chain | Residue |
| A | GLN98 |
| A | HOH492 |
| A | HOH538 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 320 |
| Chain | Residue |
| C | PHE42 |
| C | SER45 |
| C | HOH466 |
| A | ASP38 |
| A | EDO305 |
| A | HOH510 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 321 |
| Chain | Residue |
| A | PRO99 |
| A | HIS100 |
| A | ASN102 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 322 |
| Chain | Residue |
| A | GLU12 |
| A | ALA81 |
| A | GLN82 |
| A | GLY84 |
| A | ARG86 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 323 |
| Chain | Residue |
| A | THR4 |
| A | VAL5 |
| A | PHE6 |
| A | GLY9 |
| A | HIS46 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 324 |
| Chain | Residue |
| A | ARG167 |
| A | TYR168 |
| A | ASP169 |
| A | ARG222 |
| site_id | CC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG A 325 |
| Chain | Residue |
| A | ARG86 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 326 |
| Chain | Residue |
| D | GLU35 |
| D | LEU36 |
| D | MET37 |
| D | ASP38 |
| D | ASN39 |
| D | PRO40 |
| site_id | CC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 301 |
| Chain | Residue |
| A | ARG47 |
| B | GLY25 |
| B | ARG29 |
| B | ARG90 |
| B | VAL91 |
| B | GLY92 |
| B | THR93 |
| B | HOH438 |
| B | HOH497 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 302 |
| Chain | Residue |
| B | ARG86 |
| B | HOH534 |
| B | HOH551 |
| site_id | DC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 303 |
| Chain | Residue |
| B | ARG177 |
| B | HOH458 |
| B | HOH517 |
| B | HOH523 |
| D | ARG177 |
| D | PEG307 |
| D | HOH423 |
| F | ARG177 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 304 |
| Chain | Residue |
| B | LYS140 |
| B | GLN144 |
| B | EDO307 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 305 |
| Chain | Residue |
| A | ASP26 |
| A | HOH590 |
| B | HIS46 |
| site_id | DC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO B 306 |
| Chain | Residue |
| B | GLY95 |
| B | PHE161 |
| B | GLN165 |
| B | PHE194 |
| B | GLU195 |
| B | MET196 |
| B | HOH425 |
| B | HOH482 |
| B | HOH497 |
| B | HOH563 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 307 |
| Chain | Residue |
| B | GLN144 |
| B | ALA148 |
| B | THR149 |
| B | VAL150 |
| B | SO4304 |
| B | HOH564 |
| site_id | DC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EOH B 308 |
| Chain | Residue |
| B | GLY209 |
| B | HOH413 |
| B | HOH437 |
| site_id | DC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 309 |
| Chain | Residue |
| B | ALA28 |
| B | HOH477 |
| B | HOH501 |
| B | HOH561 |
| E | GLU246 |
| site_id | DC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 310 |
| Chain | Residue |
| B | GLU55 |
| B | SER60 |
| site_id | EC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 311 |
| Chain | Residue |
| B | LYS140 |
| B | HIS151 |
| B | MET152 |
| C | ASP134 |
| site_id | EC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 312 |
| Chain | Residue |
| B | GLN180 |
| B | GLY181 |
| B | LYS184 |
| B | HOH452 |
| B | HOH499 |
| B | HOH516 |
| B | HOH518 |
| site_id | EC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 313 |
| Chain | Residue |
| B | LEU115 |
| B | ARG178 |
| B | PHE179 |
| B | TRP186 |
| B | HOH431 |
| B | HOH511 |
| C | GLU126 |
| site_id | EC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 C 301 |
| Chain | Residue |
| C | GLY25 |
| C | ARG29 |
| C | ARG90 |
| C | VAL91 |
| C | GLY92 |
| C | THR93 |
| C | HOH443 |
| C | HOH610 |
| C | HOH619 |
| D | ARG47 |
| site_id | EC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K C 302 |
| Chain | Residue |
| C | GLU48 |
| C | ILE68 |
| C | SER72 |
| D | GLU48 |
| D | ILE68 |
| D | SER72 |
| site_id | EC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 303 |
| Chain | Residue |
| C | GLY95 |
| C | ARG167 |
| C | EDO307 |
| C | HOH406 |
| site_id | EC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 304 |
| Chain | Residue |
| C | ARG239 |
| C | LYS242 |
| site_id | EC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO C 305 |
| Chain | Residue |
| C | MET183 |
| C | LYS184 |
| C | GLN187 |
| C | HOH411 |
| C | HOH413 |
| C | HOH441 |
| C | HOH450 |
| F | GLN224 |
| F | LYS225 |
| site_id | EC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 306 |
| Chain | Residue |
| A | GLN180 |
| A | EDO306 |
| C | LYS184 |
| C | GLU185 |
| C | HOH611 |
| C | HOH616 |
| site_id | FC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EDO C 307 |
| Chain | Residue |
| C | PHE161 |
| C | GLN165 |
| C | PHE194 |
| C | GLU195 |
| C | MET196 |
| C | CL303 |
| C | HOH610 |
| C | HOH617 |
| C | HOH618 |
| C | HOH619 |
| D | HOH585 |
| site_id | FC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 308 |
| Chain | Residue |
| B | PHE133 |
| B | THR137 |
| C | PHE133 |
| C | THR137 |
| C | HOH437 |
| C | HOH614 |
| C | HOH627 |
| site_id | FC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 309 |
| Chain | Residue |
| B | ASP134 |
| C | LYS140 |
| C | GLN144 |
| site_id | FC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 310 |
| Chain | Residue |
| C | ASP169 |
| C | ILE227 |
| C | HOH633 |
| D | GLN82 |
| site_id | FC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EOH C 311 |
| Chain | Residue |
| C | VAL103 |
| C | THR232 |
| F | PEG312 |
| site_id | FC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG C 312 |
| Chain | Residue |
| C | HIS151 |
| C | HOH507 |
| C | HOH621 |
| site_id | FC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG C 313 |
| Chain | Residue |
| C | ASP38 |
| C | ASN39 |
| C | PRO40 |
| C | HOH629 |
| C | HOH630 |
| E | PHE42 |
| E | TYR52 |
| site_id | FC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG C 314 |
| Chain | Residue |
| C | TYR168 |
| C | GLY173 |
| E | LYS3 |
| site_id | FC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG C 315 |
| Chain | Residue |
| C | LYS225 |
| F | ASP169 |
| F | THR170 |
| F | PHE171 |
| F | THR172 |
| F | GLY173 |
| F | HOH549 |
| F | HOH570 |
| site_id | GC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG C 316 |
| Chain | Residue |
| C | ARG178 |
| C | HOH439 |
| D | LEU120 |
| D | HOH402 |
| D | HOH454 |
| site_id | GC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG C 317 |
| Chain | Residue |
| C | LEU36 |
| C | ASP38 |
| C | LEU56 |
| C | ARG249 |
| site_id | GC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 301 |
| Chain | Residue |
| C | HOH455 |
| D | HIS46 |
| D | HOH444 |
| D | HOH572 |
| site_id | GC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 302 |
| Chain | Residue |
| D | LYS140 |
| D | GLN144 |
| D | HOH520 |
| site_id | GC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 303 |
| Chain | Residue |
| D | VAL154 |
| D | MET189 |
| D | GLY190 |
| E | PHE127 |
| E | ALA206 |
| E | HOH489 |
| site_id | GC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 304 |
| Chain | Residue |
| D | PRO24 |
| D | GLY25 |
| D | ASP26 |
| D | ARG29 |
| D | GLY92 |
| D | HOH589 |
| site_id | GC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 305 |
| Chain | Residue |
| D | PHE161 |
| D | GLN165 |
| D | PHE194 |
| D | MET196 |
| D | HOH529 |
| D | HOH554 |
| D | HOH559 |
| D | HOH599 |
| site_id | GC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EOH D 306 |
| Chain | Residue |
| C | ARG47 |
| D | ARG90 |
| D | THR93 |
| D | HOH498 |
| D | HOH599 |
| site_id | GC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG D 307 |
| Chain | Residue |
| B | GLN180 |
| B | SO4303 |
| D | ARG177 |
| D | GLN180 |
| D | HOH423 |
| F | ARG177 |
| site_id | HC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG D 308 |
| Chain | Residue |
| C | GLN82 |
| C | HOH551 |
| D | ASP169 |
| D | THR170 |
| E | GLU226 |
| E | ILE227 |
| E | HOH590 |
| site_id | HC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA E 301 |
| Chain | Residue |
| E | GLU48 |
| E | ILE68 |
| E | SER72 |
| F | GLU48 |
| F | ILE68 |
| F | SER72 |
| site_id | HC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 E 302 |
| Chain | Residue |
| E | GLY92 |
| E | THR93 |
| E | HOH442 |
| E | HOH558 |
| E | HOH582 |
| F | ARG47 |
| site_id | HC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 303 |
| Chain | Residue |
| A | EDO303 |
| C | ARG177 |
| E | ARG177 |
| E | GLN180 |
| site_id | HC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 304 |
| Chain | Residue |
| E | PHE6 |
| E | ARG47 |
| E | HOH436 |
| F | HOH574 |
| site_id | HC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 305 |
| Chain | Residue |
| B | HOH446 |
| E | THR137 |
| E | ALA141 |
| E | HOH601 |
| site_id | HC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO E 306 |
| Chain | Residue |
| E | THR94 |
| E | GLY95 |
| E | PHE161 |
| E | GLN165 |
| E | ARG167 |
| E | PHE194 |
| E | HOH598 |
| site_id | HC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO E 307 |
| Chain | Residue |
| E | PRO27 |
| E | SER45 |
| E | ARG47 |
| E | THR50 |
| E | HOH458 |
| site_id | HC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO E 308 |
| Chain | Residue |
| D | MET125 |
| E | MET125 |
| E | GLU126 |
| E | HOH474 |
| site_id | IC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG E 309 |
| Chain | Residue |
| E | GLU166 |
| E | ARG167 |
| E | TYR168 |
| E | ASP169 |
| E | MET183 |
| E | ARG222 |
| E | HOH520 |
| site_id | IC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG E 310 |
| Chain | Residue |
| E | HIS46 |
| E | ARG47 |
| F | ASP26 |
| site_id | IC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG E 311 |
| Chain | Residue |
| E | LYS184 |
| E | GLN187 |
| E | HOH528 |
| site_id | IC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 F 301 |
| Chain | Residue |
| E | ARG47 |
| F | GLY25 |
| F | ARG29 |
| F | ARG90 |
| F | VAL91 |
| F | GLY92 |
| F | THR93 |
| F | HOH464 |
| F | HOH613 |
| site_id | IC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL F 302 |
| Chain | Residue |
| F | GLY95 |
| F | ARG167 |
| F | ILE220 |
| F | EDO304 |
| site_id | IC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 F 303 |
| Chain | Residue |
| A | EDO313 |
| A | HOH500 |
| F | LYS140 |
| F | GLN144 |
| F | HOH528 |
| F | HOH531 |
| site_id | IC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO F 304 |
| Chain | Residue |
| F | GLY95 |
| F | PHE161 |
| F | GLN165 |
| F | PHE194 |
| F | GLU195 |
| F | MET196 |
| F | CL302 |
| F | HOH613 |
| F | HOH617 |
| site_id | IC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO F 305 |
| Chain | Residue |
| C | LYS184 |
| C | ASP188 |
| F | ASN102 |
| F | HOH423 |
| F | HOH612 |
| site_id | IC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO F 306 |
| Chain | Residue |
| F | GLY209 |
| F | LEU210 |
| F | LYS211 |
| F | HOH467 |
| F | HOH492 |
| site_id | JC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO F 307 |
| Chain | Residue |
| E | PHE6 |
| F | PRO228 |
| F | HIS230 |
| F | LEU233 |
| F | HOH566 |
| site_id | JC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO F 308 |
| Chain | Residue |
| E | ASP26 |
| E | HOH600 |
| F | HIS46 |
| site_id | JC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO F 309 |
| Chain | Residue |
| F | ALA13 |
| F | ASN16 |
| site_id | JC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO F 310 |
| Chain | Residue |
| B | ARG177 |
| B | HOH495 |
| F | GLN180 |
| F | GLY181 |
| F | SER182 |
| F | GLU185 |
| F | HOH434 |
| site_id | JC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EOH F 311 |
| Chain | Residue |
| F | GLY9 |
| F | VAL10 |
| F | ASP14 |
| site_id | JC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG F 312 |
| Chain | Residue |
| C | GLN224 |
| C | ASP229 |
| C | EOH311 |
| F | TYR168 |
| F | HOH552 |
| site_id | JC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG F 313 |
| Chain | Residue |
| F | GLY9 |
| F | HIS46 |
| F | HOH529 |
| site_id | JC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG F 314 |
| Chain | Residue |
| A | SER208 |
| A | GLY209 |
| A | HOH413 |
| B | ARG174 |
| F | ASP188 |
| F | GLY190 |
| F | PEG318 |
| F | HOH512 |
| site_id | JC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG F 315 |
| Chain | Residue |
| F | PHE42 |
| F | SER45 |
| F | THR50 |
| F | HOH523 |
| F | HOH551 |
| site_id | KC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG F 316 |
| Chain | Residue |
| F | GLU35 |
| F | LEU36 |
| F | MET37 |
| site_id | KC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG F 317 |
| Chain | Residue |
| F | GLN144 |
| F | GLU145 |
| F | HOH550 |
| F | HOH606 |
| site_id | KC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG F 318 |
| Chain | Residue |
| F | GLN98 |
| F | GLN187 |
| F | ASP188 |
| F | PEG314 |
| F | HOH577 |
Functional Information from PROSITE/UniProt
| site_id | PS01232 |
| Number of Residues | 16 |
| Details | PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL |
| Chain | Residue | Details |
| A | SER65-LEU80 |
