Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0032787 | biological_process | monocarboxylic acid metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0032787 | biological_process | monocarboxylic acid metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0032787 | biological_process | monocarboxylic acid metabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0032787 | biological_process | monocarboxylic acid metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 301 |
| Chain | Residue |
| A | ALA96 |
| A | ASP101 |
| A | HOH407 |
| A | HOH412 |
| A | HOH415 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| Chain | Residue |
| D | GLY254 |
| A | LYS163 |
| A | SER166 |
| A | LYS167 |
| D | PRO219 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 303 |
| Chain | Residue |
| A | GLY20 |
| A | GLU187 |
| A | CL306 |
| A | HOH514 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 304 |
| Chain | Residue |
| A | LEU144 |
| A | PRO145 |
| A | GLU146 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 305 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL A 306 |
| Chain | Residue |
| A | LYS19 |
| A | THR186 |
| A | GLU187 |
| A | ALA188 |
| A | CL303 |
| A | HOH559 |
| A | HOH570 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 307 |
| Chain | Residue |
| A | MSE212 |
| A | GLY217 |
| A | ILE218 |
| A | HOH478 |
| A | HOH524 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 308 |
| Chain | Residue |
| A | ARG118 |
| A | GLN119 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 309 |
| Chain | Residue |
| A | LYS167 |
| A | HOH530 |
| D | HOH611 |
| D | HOH690 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 310 |
| Chain | Residue |
| A | VAL141 |
| B | ALA259 |
| B | CL307 |
| B | HOH545 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 311 |
| Chain | Residue |
| A | ASP99 |
| A | HOH425 |
| C | HOH515 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 312 |
| Chain | Residue |
| A | GLY130 |
| A | GLY173 |
| A | HOH488 |
| A | HOH561 |
| A | HOH623 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 313 |
| Chain | Residue |
| A | ARG115 |
| A | ARG118 |
| A | HOH448 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 314 |
| Chain | Residue |
| A | PHE4 |
| A | LEU5 |
| C | SER-1 |
| D | PHE4 |
| D | LEU5 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 315 |
| Chain | Residue |
| A | THR15 |
| A | HIS82 |
| A | HOH413 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD A 316 |
| Chain | Residue |
| A | GLN139 |
| A | TRP183 |
| A | MPD318 |
| A | HOH581 |
| A | HOH597 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MPD A 317 |
| Chain | Residue |
| A | MSE83 |
| A | LEU84 |
| A | GLY85 |
| A | GLY86 |
| A | VAL135 |
| A | TYR151 |
| A | LYS155 |
| A | ILE184 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 318 |
| Chain | Residue |
| A | GLY86 |
| A | SER87 |
| A | SER189 |
| A | MPD316 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CA B 301 |
| Chain | Residue |
| B | ALA96 |
| B | ASP101 |
| B | CA303 |
| B | HOH409 |
| B | HOH421 |
| B | HOH456 |
| B | HOH509 |
| B | HOH615 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 302 |
| Chain | Residue |
| B | LYS163 |
| B | GLY246 |
| C | VAL256 |
| C | THR258 |
| C | HOH417 |
| C | HOH420 |
| C | HOH470 |
| site_id | CC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 303 |
| Chain | Residue |
| B | SER98 |
| B | ASP101 |
| B | CA301 |
| B | HOH434 |
| B | HOH509 |
| B | HOH529 |
| B | HOH615 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 304 |
| Chain | Residue |
| B | LYS163 |
| B | SER166 |
| B | LYS167 |
| C | PRO219 |
| C | GLY254 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 305 |
| Chain | Residue |
| B | THR15 |
| B | HIS82 |
| B | HOH402 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 306 |
| Chain | Residue |
| B | GLY20 |
| B | GLU187 |
| B | HOH566 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 307 |
| Chain | Residue |
| A | CL310 |
| A | HOH435 |
| B | ALA259 |
| C | ARG140 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 308 |
| Chain | Residue |
| B | ARG43 |
| B | VAL53 |
| B | GLU54 |
| B | HOH589 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 309 |
| Chain | Residue |
| B | ARG115 |
| B | ARG118 |
| B | HOH579 |
| site_id | DC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 310 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 311 |
| Chain | Residue |
| B | ILE2 |
| B | PHE4 |
| B | LEU5 |
| C | PHE4 |
| C | LEU5 |
| D | SER-1 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 312 |
| Chain | Residue |
| B | LEU144 |
| B | PRO145 |
| B | GLU146 |
| B | HOH560 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD B 313 |
| Chain | Residue |
| B | GLN139 |
| B | TRP183 |
| B | MPD314 |
| B | HOH552 |
| B | HOH616 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD B 314 |
| Chain | Residue |
| B | GLY86 |
| B | SER87 |
| B | MPD313 |
| B | HOH555 |
| site_id | DC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MPD B 315 |
| Chain | Residue |
| B | MSE83 |
| B | GLY85 |
| B | GLY86 |
| B | THR136 |
| B | TYR151 |
| B | LYS155 |
| B | ILE184 |
| B | HOH465 |
| site_id | DC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA C 301 |
| Chain | Residue |
| C | ALA96 |
| C | ASP101 |
| C | HOH437 |
| C | HOH441 |
| C | HOH449 |
| C | HOH522 |
| C | HOH572 |
| site_id | DC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA C 302 |
| Chain | Residue |
| C | GLY216 |
| C | GLY217 |
| C | THR255 |
| C | HOH433 |
| C | HOH444 |
| C | HOH531 |
| C | HOH557 |
| site_id | DC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA C 303 |
| Chain | Residue |
| C | ILE184 |
| C | THR186 |
| C | SER189 |
| C | CL310 |
| C | MPD315 |
| C | HOH570 |
| C | HOH590 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 304 |
| Chain | Residue |
| C | LYS163 |
| C | SER166 |
| C | LYS167 |
| site_id | EC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL C 305 |
| Chain | Residue |
| C | THR186 |
| C | GLU187 |
| C | ALA188 |
| C | CL309 |
| C | HOH578 |
| C | HOH579 |
| site_id | EC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 306 |
| Chain | Residue |
| B | HOH436 |
| B | HOH536 |
| C | LYS167 |
| C | HOH508 |
| C | HOH656 |
| site_id | EC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 307 |
| Chain | Residue |
| B | ARG140 |
| C | ALA259 |
| C | HOH646 |
| D | VAL141 |
| D | HOH541 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 308 |
| Chain | Residue |
| A | GLU185 |
| A | HOH549 |
| C | ASP203 |
| C | LEU204 |
| site_id | EC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 309 |
| Chain | Residue |
| C | GLY20 |
| C | GLU187 |
| C | CL305 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 310 |
| Chain | Residue |
| C | ILE184 |
| C | CA303 |
| C | MPD315 |
| C | HOH564 |
| site_id | EC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 311 |
| Chain | Residue |
| C | THR15 |
| C | HIS82 |
| C | HOH411 |
| site_id | EC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 312 |
| Chain | Residue |
| A | HOH603 |
| C | LEU144 |
| C | PRO145 |
| C | GLU146 |
| site_id | FC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD C 313 |
| Chain | Residue |
| C | GLN139 |
| C | LEU144 |
| C | MPD315 |
| C | HOH563 |
| C | HOH628 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD C 314 |
| Chain | Residue |
| A | ASP99 |
| A | TYR103 |
| C | PHE111 |
| C | ARG115 |
| site_id | FC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD C 315 |
| Chain | Residue |
| C | GLY86 |
| C | SER87 |
| C | SER189 |
| C | CA303 |
| C | CL310 |
| C | MPD313 |
| C | HOH649 |
| site_id | FC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MPD C 316 |
| Chain | Residue |
| C | GLY85 |
| C | GLY86 |
| C | THR136 |
| C | TYR151 |
| C | LYS155 |
| C | HOH565 |
| C | HOH573 |
| C | HOH585 |
| C | HOH657 |
| site_id | FC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA D 301 |
| Chain | Residue |
| D | ALA96 |
| D | ASP101 |
| D | HOH526 |
| D | HOH532 |
| D | HOH586 |
| D | HOH726 |
| D | HOH735 |
| site_id | FC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 302 |
| Chain | Residue |
| B | HOH439 |
| B | HOH613 |
| D | HOH542 |
| D | HOH550 |
| D | HOH577 |
| D | HOH648 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 303 |
| Chain | Residue |
| D | GLY216 |
| D | HOH528 |
| D | HOH548 |
| D | HOH597 |
| D | HOH719 |
| site_id | FC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 304 |
| Chain | Residue |
| D | GLY173 |
| D | HOH561 |
| D | HOH600 |
| D | HOH628 |
| D | HOH686 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 305 |
| Chain | Residue |
| D | LYS163 |
| D | SER166 |
| D | LYS167 |
| site_id | GC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 306 |
| Chain | Residue |
| D | THR186 |
| D | GLU187 |
| D | ALA188 |
| D | CL310 |
| site_id | GC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 307 |
| Chain | Residue |
| D | THR15 |
| D | HIS82 |
| D | HOH658 |
| site_id | GC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL D 308 |
| site_id | GC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 309 |
| Chain | Residue |
| D | GLY76 |
| D | VAL77 |
| D | ARG127 |
| D | HOH547 |
| D | HOH668 |
| site_id | GC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 310 |
| Chain | Residue |
| D | GLY20 |
| D | GLU187 |
| D | CL306 |
| site_id | GC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 311 |
| site_id | GC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL D 312 |
| Chain | Residue |
| D | ARG115 |
| D | ARG118 |
| D | HOH501 |
| D | HOH537 |
| D | HOH704 |
| site_id | GC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD D 313 |
| Chain | Residue |
| D | GLN139 |
| D | MPD314 |
| D | HOH656 |
| D | HOH731 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD D 314 |
| Chain | Residue |
| D | GLY86 |
| D | SER87 |
| D | SER189 |
| D | MPD313 |
| D | HOH676 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. IqrvlplpesTtaYAAAKAALsTYSkAMS |
| Chain | Residue | Details |
| A | ILE138-SER166 | |
