4H0S
Crystal structure analysis of a basic phospholipase A2 from Trimeresurus stejnegeri venom
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004623 | molecular_function | phospholipase A2 activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0006644 | biological_process | phospholipid metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0050482 | biological_process | arachidonic acid secretion |
| B | 0004623 | molecular_function | phospholipase A2 activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006644 | biological_process | phospholipid metabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0050482 | biological_process | arachidonic acid secretion |
| C | 0004623 | molecular_function | phospholipase A2 activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0006644 | biological_process | phospholipid metabolic process |
| C | 0016042 | biological_process | lipid catabolic process |
| C | 0050482 | biological_process | arachidonic acid secretion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 201 |
| Chain | Residue |
| A | TRP77 |
| A | HOH315 |
| B | HOH378 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 202 |
| Chain | Residue |
| A | GLU17 |
| B | ASN79 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 201 |
| Chain | Residue |
| B | LYS7 |
| B | TYR75 |
| B | TRP77 |
| B | HOH331 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 202 |
| Chain | Residue |
| B | GLU17 |
| B | ILE19 |
| B | LEU20 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA C 201 |
| Chain | Residue |
| C | GLN4 |
| C | LYS7 |
Functional Information from PROSITE/UniProt
| site_id | PS00118 |
| Number of Residues | 8 |
| Details | PA2_HIS Phospholipase A2 histidine active site. CCSiHNcC |
| Chain | Residue | Details |
| A | CYS44-CYS51 |
| site_id | PS00119 |
| Number of Residues | 11 |
| Details | PA2_ASP Phospholipase A2 aspartic acid active site. VCECDKAVaTC |
| Chain | Residue | Details |
| A | VAL95-CYS105 |
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. SCSTkwDsYSYSWEN |
| Chain | Residue | Details |
| A | SER59-ASN79 |
