4H0L
Cytochrome b6f Complex Crystal Structure from Mastigocladus laminosus with n-Side Inhibitor NQNO
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0009579 | cellular_component | thylakoid |
| A | 0015979 | biological_process | photosynthesis |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0022904 | biological_process | respiratory electron transport chain |
| A | 0031676 | cellular_component | plasma membrane-derived thylakoid membrane |
| A | 0042651 | cellular_component | thylakoid membrane |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008121 | molecular_function | ubiquinol-cytochrome-c reductase activity |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0009579 | cellular_component | thylakoid |
| B | 0009767 | biological_process | photosynthetic electron transport chain |
| B | 0015979 | biological_process | photosynthesis |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0031676 | cellular_component | plasma membrane-derived thylakoid membrane |
| B | 0042651 | cellular_component | thylakoid membrane |
| B | 1902600 | biological_process | proton transmembrane transport |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0009579 | cellular_component | thylakoid |
| C | 0015979 | biological_process | photosynthesis |
| C | 0016020 | cellular_component | membrane |
| C | 0020037 | molecular_function | heme binding |
| C | 0031676 | cellular_component | plasma membrane-derived thylakoid membrane |
| C | 0042651 | cellular_component | thylakoid membrane |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0009496 | molecular_function | plastoquinol--plastocyanin reductase activity |
| D | 0009579 | cellular_component | thylakoid |
| D | 0015979 | biological_process | photosynthesis |
| D | 0016020 | cellular_component | membrane |
| D | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| D | 0031676 | cellular_component | plasma membrane-derived thylakoid membrane |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| D | 0055085 | biological_process | transmembrane transport |
| E | 0009055 | molecular_function | electron transfer activity |
| E | 0009512 | cellular_component | cytochrome b6f complex |
| E | 0009579 | cellular_component | thylakoid |
| E | 0015979 | biological_process | photosynthesis |
| E | 0016020 | cellular_component | membrane |
| E | 0031676 | cellular_component | plasma membrane-derived thylakoid membrane |
| E | 0042651 | cellular_component | thylakoid membrane |
| F | 0009055 | molecular_function | electron transfer activity |
| F | 0009512 | cellular_component | cytochrome b6f complex |
| F | 0009579 | cellular_component | thylakoid |
| F | 0015979 | biological_process | photosynthesis |
| F | 0016020 | cellular_component | membrane |
| F | 0031676 | cellular_component | plasma membrane-derived thylakoid membrane |
| F | 0042651 | cellular_component | thylakoid membrane |
| G | 0009512 | cellular_component | cytochrome b6f complex |
| G | 0009579 | cellular_component | thylakoid |
| G | 0015979 | biological_process | photosynthesis |
| G | 0016020 | cellular_component | membrane |
| G | 0017004 | biological_process | cytochrome complex assembly |
| G | 0031676 | cellular_component | plasma membrane-derived thylakoid membrane |
| G | 0042651 | cellular_component | thylakoid membrane |
| H | 0009055 | molecular_function | electron transfer activity |
| H | 0009512 | cellular_component | cytochrome b6f complex |
| H | 0009579 | cellular_component | thylakoid |
| H | 0015979 | biological_process | photosynthesis |
| H | 0016020 | cellular_component | membrane |
| H | 0017004 | biological_process | cytochrome complex assembly |
| H | 0031676 | cellular_component | plasma membrane-derived thylakoid membrane |
| H | 0042651 | cellular_component | thylakoid membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 301 |
| Chain | Residue |
| A | GLU75 |
| A | HOH401 |
| C | LYS140 |
| C | HIS143 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM A 302 |
| Chain | Residue |
| A | HIS86 |
| A | ARG87 |
| A | ALA90 |
| A | MET93 |
| A | PHE131 |
| A | GLY135 |
| A | LEU138 |
| A | PRO139 |
| A | HIS187 |
| A | THR188 |
| A | PHE189 |
| A | GLN47 |
| A | GLY51 |
| A | PHE52 |
| A | MET54 |
| A | ARG83 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HEM A 303 |
| Chain | Residue |
| A | TYR34 |
| A | GLY37 |
| A | GLY38 |
| A | MET93 |
| A | HIS100 |
| A | VAL101 |
| A | ARG103 |
| A | VAL104 |
| A | GLY109 |
| A | ARG114 |
| A | THR117 |
| A | TRP118 |
| A | GLY121 |
| A | VAL122 |
| A | ALA125 |
| A | HIS202 |
| A | PHE203 |
| A | ILE206 |
| A | ILE211 |
| A | SER212 |
| A | HEM304 |
| A | HOH402 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM A 304 |
| Chain | Residue |
| A | VAL30 |
| A | TYR34 |
| A | CYS35 |
| A | GLY38 |
| A | LEU41 |
| A | PHE203 |
| A | ILE206 |
| A | ARG207 |
| A | GLY210 |
| A | ILE211 |
| A | HEM303 |
| A | QNO308 |
| A | HOH402 |
| B | ASN25 |
| B | VAL39 |
| B | PHE40 |
| H | ARG26 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OPC A 305 |
| Chain | Residue |
| A | MET92 |
| B | CYS50 |
| C | GLN38 |
| E | TYR8 |
| F | GLU3 |
| F | TYR7 |
| F | VAL18 |
| G | LEU5 |
| G | LEU9 |
| G | BCR101 |
| H | TRP8 |
| H | PHE15 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE UMQ A 306 |
| Chain | Residue |
| A | LEU12 |
| A | ASP20 |
| A | LYS24 |
| A | LYS208 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE UMQ A 307 |
| Chain | Residue |
| A | TYR5 |
| A | ASP6 |
| A | ILE14 |
| A | GLN15 |
| A | UMQ309 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE QNO A 308 |
| Chain | Residue |
| A | LYS24 |
| A | ARG207 |
| A | HEM304 |
| B | LEU36 |
| B | PHE40 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE UMQ A 309 |
| Chain | Residue |
| A | UMQ307 |
| B | TRP32 |
| C | GLU286 |
| D | SQD201 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 201 |
| Chain | Residue |
| B | ASP58 |
| C | LYS146 |
| F | GLU4 |
| site_id | BC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CLA B 202 |
| Chain | Residue |
| B | LEU108 |
| B | ILE132 |
| B | PHE133 |
| B | GLY136 |
| B | THR140 |
| B | OPC203 |
| B | HOH301 |
| B | HOH303 |
| A | TYR105 |
| B | TYR80 |
| B | VAL84 |
| B | ILE87 |
| B | MET101 |
| B | VAL104 |
| B | PRO105 |
| site_id | BC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OPC B 203 |
| Chain | Residue |
| A | TYR105 |
| B | LEU100 |
| B | SER103 |
| B | VAL111 |
| B | ILE114 |
| B | GLU115 |
| B | ASN118 |
| B | ARG126 |
| B | PRO127 |
| B | VAL128 |
| B | ALA129 |
| B | CLA202 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE UMQ C 301 |
| Chain | Residue |
| A | ASN74 |
| A | GLU75 |
| A | TRP80 |
| C | ASP251 |
| C | ASN253 |
| C | TRP257 |
| D | GLY33 |
| D | ALA34 |
| D | PRO37 |
| site_id | BC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM C 302 |
| Chain | Residue |
| C | TYR1 |
| C | PRO2 |
| C | TRP4 |
| C | ALA5 |
| C | CYS22 |
| C | CYS25 |
| C | HIS26 |
| C | GLN60 |
| C | LEU70 |
| C | ASN71 |
| C | VAL72 |
| C | GLY73 |
| C | ALA74 |
| C | ASN154 |
| C | GLY156 |
| C | ARG157 |
| C | GLY158 |
| C | ILE160 |
| C | TYR161 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FES D 200 |
| Chain | Residue |
| D | CYS108 |
| D | HIS110 |
| D | LEU111 |
| D | CYS126 |
| D | HIS129 |
| D | GLY130 |
| D | SER131 |
| site_id | BC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SQD D 201 |
| Chain | Residue |
| A | UMQ309 |
| B | TRP32 |
| B | PRO33 |
| B | LEU37 |
| B | TYR38 |
| C | LYS275 |
| C | VAL279 |
| D | ARG16 |
| D | ASN20 |
| D | PHE24 |
| D | GLY25 |
| D | THR28 |
| site_id | BC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE BCR G 101 |
| Chain | Residue |
| A | ILE32 |
| A | PHE33 |
| A | ILE39 |
| A | MET96 |
| A | LEU99 |
| A | OPC305 |
| F | ILE16 |
| F | PHE17 |
| F | TRP20 |
| G | ALA16 |
| G | GLY19 |
| G | GLY20 |
| G | TYR23 |
| H | PHE15 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_00395, ECO:0000305|PubMed:14526088 |
| Chain | Residue | Details |
| H | ILE3-VAL23 | |
| B | ASN116-THR130 | |
| A | ARG207-LEU215 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical => ECO:0000305|PubMed:14526088 |
| Chain | Residue | Details |
| D | LEU21-ILE43 | |
| B | LEU95-GLU115 | |
| B | THR131-LEU151 | |
| A | ALA186-ILE206 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 135 |
| Details | TOPO_DOM: Lumenal, thylakoid => ECO:0000305|PubMed:14526088 |
| Chain | Residue | Details |
| D | PRO44-VAL179 | |
| C | HIS26 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14526088 |
| Chain | Residue | Details |
| D | CYS108 | |
| D | HIS110 | |
| D | CYS126 | |
| D | HIS129 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14526088, ECO:0000269|PubMed:16371475, ECO:0007744|PDB:1VF5, ECO:0007744|PDB:2D2C |
| Chain | Residue | Details |
| A | ARG83 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | BINDING: axial binding residue => ECO:0000269|PubMed:14526088, ECO:0000269|PubMed:16371475, ECO:0007744|PDB:1VF5, ECO:0007744|PDB:2D2C |
| Chain | Residue | Details |
| A | HIS86 | |
| A | HIS100 | |
| A | HIS187 | |
| A | HIS202 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14526088, ECO:0007744|PDB:1VF5 |
| Chain | Residue | Details |
| A | ARG103 | |
| A | LYS208 |
