4GZ7
The crystal structure of Apo-dihydropyrimidinase from Tetraodon nigroviridis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004157 | molecular_function | dihydropyrimidinase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| A | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MHA A 601 |
| Chain | Residue |
| A | HIS65 |
| A | HOH758 |
| A | HOH803 |
| A | HOH810 |
| A | LEU68 |
| A | HIS244 |
| A | MET293 |
| A | GLY294 |
| A | ASP322 |
| A | ASN343 |
| A | GLY344 |
| A | MHA602 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MHA A 602 |
| Chain | Residue |
| A | PHE70 |
| A | TYR160 |
| A | PHE164 |
| A | THR339 |
| A | ILE341 |
| A | PRO342 |
| A | ASN343 |
| A | MHA601 |
| A | MHA603 |
| A | HOH813 |
| A | HOH851 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MHA A 603 |
| Chain | Residue |
| A | ILE195 |
| A | ALA199 |
| A | HIS213 |
| A | CYS216 |
| A | ARG217 |
| A | PHE338 |
| A | THR339 |
| A | ASN343 |
| A | MHA602 |
| A | HOH837 |
| A | HOH864 |
| A | HOH884 |
