English 日本語简体中文繁體中文 한국어

✖

Menu

RCSB PDB PDBe BMRB Adv. Search Search help

Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4GY7

Crystallographic structure analysis of urease from Jack bean (Canavalia ensiformis) at 1.49 A Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009039	molecular_function	urease activity
A	0016151	molecular_function	nickel cation binding
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0035550	cellular_component	urease complex
A	0035821	biological_process	modulation of process of another organism
A	0043419	biological_process	urea catabolic process
A	0046872	molecular_function	metal ion binding
A	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NI A 901

Chain	Residue
A	KCX490
A	HIS492
A	HIS519
A	HIS545
A	GLY550
A	NI902
A	PO4903

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI A 902

Chain	Residue
A	KCX490
A	ASP633
A	NI901
A	PO4903
A	HIS407
A	HIS409

site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE PO4 A 903

Chain	Residue
A	HIS407
A	HIS409
A	ALA440
A	KCX490
A	HIS492
A	HIS519
A	HIS545
A	GLY550
A	ASP633
A	ALA636
A	MET637
A	NI901
A	NI902

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 904

Chain	Residue
A	ASN193
A	ILE194
A	VAL200
A	VAL210
A	THR211
A	HOH1528
A	HOH1757

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 905

Chain	Residue
A	PRO5
A	TYR417
A	ACN916
A	HOH1122
A	HOH1322
A	HOH1531
A	HOH1543
A	HOH1810

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 906

Chain	Residue
A	GLU9
A	GLN414
A	MET746
A	ARG747
A	HOH1322
A	HOH1533
A	HOH1744

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 907

Chain	Residue
A	GLY538
A	THR540
A	ARG791
A	LYS792
A	LEU793
A	HOH1727

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 908

Chain	Residue
A	PRO178
A	TYR179
A	GLY248
A	EDO912
A	HOH1741
A	HOH1750

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 909

Chain	Residue
A	ALA196
A	LYS282
A	VAL314
A	LYS319
A	HOH1413
A	HOH1756
A	HOH1809

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 910

Chain	Residue
A	VAL118
A	PRO119
A	SER120
A	SER258
A	HOH1305
A	HOH1638
A	HOH1861

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 911

Chain	Residue
A	ASN225
A	KCX247
A	PRO499
A	ASP503
A	HOH1170
A	HOH1229

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 912

Chain	Residue
A	TYR179
A	GLU530
A	HIS531
A	EDO908

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 913

Chain	Residue
A	GLN692
A	TYR693
A	ALA786
A	HOH1044
A	HOH1199
A	HOH1352
A	HOH1414

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACN A 914

Chain	Residue
A	SER813
A	THR815
A	HOH1541

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACN A 915

Chain	Residue
A	HOH1755
A	GLN166
A	GLY317
A	HIS593
A	PHE605
A	HOH1251

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACN A 916

Chain	Residue
A	EDO905
A	HOH1543
A	HOH1744
A	HOH1795

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACN A 917

Chain	Residue
A	GLN82
A	ARG439
A	VAL591
A	ILE738
A	THR740

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACN A 918

Chain	Residue
A	GLN166
A	ALA199
A	GLU601
A	ASP602

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BME A 919

Chain	Residue
A	GLY316
A	GLY317
A	ASP494
A	CME592
A	HOH1646
A	HOH1753

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 920

Chain	Residue
A	TYR417
A	LEU460
A	PRO461
A	TRP728
A	THR752
A	HOH1005
A	HOH1795

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 921

Chain	Residue
A	ARG26
A	GLY27
A	ASP49
A	HOH1599

site_id	CC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO A 922

Chain	Residue
A	GLY362
A	LEU702
A	GLY723
A	ALA759
A	LEU760
A	ARG783
A	HOH1264
A	HOH1758
A	HOH1761

site_id	CC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 A 923

Chain	Residue
A	HIS511
A	HIS512
A	LYS767
A	ALA768
A	ASP771
A	HOH1035
A	HOH1466
A	HOH1804

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 924

Chain	Residue
A	PRO164
A	PRO811
A	HOH1319

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 925

Chain	Residue
A	ALA828
A	THR829
A	HOH1552

Functional Information from PROSITE/UniProt

site_id	PS00145
Number of Residues	17
Details	UREASE_2 Urease active site. MVCHHLdreIpeDLaFA

Chain	Residue	Details
A	MET590-ALA606

site_id	PS01120
Number of Residues	14
Details	UREASE_1 Urease nickel ligands signature. TAGAIDcHVHyicP

Chain	Residue	Details
A	THR400-PRO413

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000250

Chain	Residue	Details
A	HIS593

site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269\|PubMed:20471401, ECO:0007744\|PDB:3LA4, ECO:0007744\|PDB:4GOA, ECO:0007744\|PDB:4GY7, ECO:0007744\|PDB:4H9M

Chain	Residue	Details
A	HIS407
A	HIS409
A	HIS519
A	HIS545
A	ASP633

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: via carbamate group => ECO:0000269\|PubMed:20471401, ECO:0007744\|PDB:3LA4, ECO:0007744\|PDB:4GOA, ECO:0007744\|PDB:4GY7, ECO:0007744\|PDB:4H9M

Chain	Residue	Details
A	KCX490

site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	HIS492

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-carboxylysine => ECO:0000269\|PubMed:20471401

Chain	Residue	Details
A	KCX490

225946

PDB entries from 2024-10-09

PDB statistics

PDBj update info

Contact PDBj

numon