4GVX
Crystal structure of a short chain dehydrogenase homolog (target EFI-505321) from burkholderia multivorans, with bound NADP and L-fucose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019317 | biological_process | fucose catabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| B | 0006004 | biological_process | fucose metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019317 | biological_process | fucose catabolic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| C | 0006004 | biological_process | fucose metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019317 | biological_process | fucose catabolic process |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| D | 0006004 | biological_process | fucose metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019317 | biological_process | fucose catabolic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:A7IQH5 |
| Chain | Residue | Details |
| A | TYR153 | |
| B | TYR153 | |
| C | TYR153 | |
| D | TYR153 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 68 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23214453, ECO:0007744|PDB:4GVX |
| Chain | Residue | Details |
| A | SER17 | |
| A | LYS141 | |
| A | GLN147 | |
| A | TYR153 | |
| A | LYS157 | |
| A | ALA184 | |
| A | GLU185 | |
| A | VAL186 | |
| A | THR188 | |
| B | SER17 | |
| B | ILE19 | |
| A | ILE19 | |
| B | ARG39 | |
| B | HIS40 | |
| B | GLU63 | |
| B | LEU64 | |
| B | ASN90 | |
| B | ASN94 | |
| B | SER140 | |
| B | LYS141 | |
| B | GLN147 | |
| B | TYR153 | |
| A | ARG39 | |
| B | LYS157 | |
| B | ALA184 | |
| B | GLU185 | |
| B | VAL186 | |
| B | THR188 | |
| C | SER17 | |
| C | ILE19 | |
| C | ARG39 | |
| C | HIS40 | |
| C | GLU63 | |
| A | HIS40 | |
| C | LEU64 | |
| C | ASN90 | |
| C | ASN94 | |
| C | SER140 | |
| C | LYS141 | |
| C | GLN147 | |
| C | TYR153 | |
| C | LYS157 | |
| C | ALA184 | |
| C | GLU185 | |
| A | GLU63 | |
| C | VAL186 | |
| C | THR188 | |
| D | SER17 | |
| D | ILE19 | |
| D | ARG39 | |
| D | HIS40 | |
| D | GLU63 | |
| D | LEU64 | |
| D | ASN90 | |
| D | ASN94 | |
| A | LEU64 | |
| D | SER140 | |
| D | LYS141 | |
| D | GLN147 | |
| D | TYR153 | |
| D | LYS157 | |
| D | ALA184 | |
| D | GLU185 | |
| D | VAL186 | |
| D | THR188 | |
| A | ASN90 | |
| A | ASN94 | |
| A | SER140 |
