Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4GUV

TetX derivatized with Xenon

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004497	molecular_function	monooxygenase activity
A	0005737	cellular_component	cytoplasm
A	0016491	molecular_function	oxidoreductase activity
A	0046677	biological_process	response to antibiotic
A	0071949	molecular_function	FAD binding
B	0000166	molecular_function	nucleotide binding
B	0004497	molecular_function	monooxygenase activity
B	0005737	cellular_component	cytoplasm
B	0016491	molecular_function	oxidoreductase activity
B	0046677	biological_process	response to antibiotic
B	0071949	molecular_function	FAD binding
C	0000166	molecular_function	nucleotide binding
C	0004497	molecular_function	monooxygenase activity
C	0005737	cellular_component	cytoplasm
C	0016491	molecular_function	oxidoreductase activity
C	0046677	biological_process	response to antibiotic
C	0071949	molecular_function	FAD binding
D	0000166	molecular_function	nucleotide binding
D	0004497	molecular_function	monooxygenase activity
D	0005737	cellular_component	cytoplasm
D	0016491	molecular_function	oxidoreductase activity
D	0046677	biological_process	response to antibiotic
D	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	BINDING SITE FOR RESIDUE FAD A 401

Chain	Residue
A	GLY23
A	LEU60
A	ARG117
A	ARG121
A	ARG137
A	LYS138
A	LEU139
A	ALA167
A	ASN168
A	GLY169
A	GLN192
A	GLY24
A	GLY310
A	ASP311
A	PRO318
A	GLN322
A	GLY323
A	VAL324
A	HOH506
A	GLY25
A	PRO26
A	VAL27
A	TYR45
A	GLU46
A	ARG47
A	ASP48

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 402

Chain	Residue
A	ARG137
A	LYS156

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 403

Chain	Residue
A	LYS138
A	LYS173

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE XE A 404

Chain	Residue
A	ILE237
A	PHE267
A	TYR274

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE XE A 405

Chain	Residue
A	ASN221
A	PHE239
A	GLU266

site_id	AC6
Number of Residues	26
Details	BINDING SITE FOR RESIDUE FAD B 401

Chain	Residue
B	GLY23
B	GLY25
B	PRO26
B	VAL27
B	TYR45
B	GLU46
B	ARG47
B	ASP48
B	LEU60
B	ARG117
B	ARG121
B	ARG137
B	LYS138
B	LEU139
B	ALA167
B	ASN168
B	GLY169
B	GLN192
B	LEU287
B	GLY310
B	ASP311
B	PRO318
B	GLN322
B	GLY323
B	VAL324
B	HOH506

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 B 402

Chain	Residue
B	ARG54

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 403

Chain	Residue
B	ARG137
B	LYS156

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 404

Chain	Residue
B	ARG47
B	LYS138

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE XE B 405

Chain	Residue
B	LEU223
B	ILE237
B	PHE267
B	TYR274
B	ILE278

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE XE B 406

Chain	Residue
B	ASN221
B	PHE239
B	GLU266

site_id	BC3
Number of Residues	24
Details	BINDING SITE FOR RESIDUE FAD C 401

Chain	Residue
C	GLY23
C	GLY25
C	PRO26
C	VAL27
C	TYR45
C	GLU46
C	ARG47
C	ASP48
C	LEU60
C	ARG117
C	ARG121
C	ARG137
C	LYS138
C	LEU139
C	ALA167
C	ASN168
C	GLY169
C	LEU287
C	GLY310
C	ASP311
C	PRO318
C	GLN322
C	GLY323
C	VAL324

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 402

Chain	Residue
C	GLU52
C	ALA53
C	ARG54

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 403

Chain	Residue
C	ARG137
C	LYS156

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 C 404

Chain	Residue
C	LYS138

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE XE C 405

Chain	Residue
C	ILE237
C	PHE267
C	TYR274

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE XE C 406

Chain	Residue
C	PHE239
C	GLU266
C	PHE267

site_id	BC9
Number of Residues	25
Details	BINDING SITE FOR RESIDUE FAD D 401

Chain	Residue
D	GLY23
D	GLY25
D	PRO26
D	VAL27
D	TYR45
D	GLU46
D	ARG47
D	ASP48
D	LEU60
D	ARG117
D	ARG121
D	ARG137
D	LYS138
D	LEU139
D	ALA167
D	ASN168
D	GLY169
D	GLN192
D	LEU287
D	GLY310
D	ASP311
D	PRO318
D	GLN322
D	GLY323
D	VAL324

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 D 402

Chain	Residue
D	ARG54

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 403

Chain	Residue
D	ARG137
D	LYS156

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 404

Chain	Residue
D	ARG47
D	HOH511

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE XE D 405

Chain	Residue
D	LEU223
D	ILE237
D	PHE267

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE XE D 406

Chain	Residue
D	ASN221
D	PHE239
D	GLU266
D	PHE267

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21590745","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XDO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A6N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GUV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00845","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00845","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"3V3O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00845","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21590745","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XDO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A6N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GUV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23999299","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2Y6Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A99","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21402075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23999299","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2Y6Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3V3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A6N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4A99","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)