4GT2

Crystal structure of DyP-type peroxidase (SCO3963) from Streptomyces coelicolor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004325	molecular_function	ferrochelatase activity
A	0004601	molecular_function	peroxidase activity
A	0005829	cellular_component	cytosol
A	0016491	molecular_function	oxidoreductase activity
A	0016829	molecular_function	lyase activity
A	0020037	molecular_function	heme binding
A	0030313	cellular_component	cell envelope
A	0033212	biological_process	iron import into cell
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification
B	0004325	molecular_function	ferrochelatase activity
B	0004601	molecular_function	peroxidase activity
B	0005829	cellular_component	cytosol
B	0016491	molecular_function	oxidoreductase activity
B	0016829	molecular_function	lyase activity
B	0020037	molecular_function	heme binding
B	0030313	cellular_component	cell envelope
B	0033212	biological_process	iron import into cell
B	0046872	molecular_function	metal ion binding
B	0098869	biological_process	cellular oxidant detoxification
E	0004325	molecular_function	ferrochelatase activity
E	0004601	molecular_function	peroxidase activity
E	0005829	cellular_component	cytosol
E	0016491	molecular_function	oxidoreductase activity
E	0016829	molecular_function	lyase activity
E	0020037	molecular_function	heme binding
E	0030313	cellular_component	cell envelope
E	0033212	biological_process	iron import into cell
E	0046872	molecular_function	metal ion binding
E	0098869	biological_process	cellular oxidant detoxification
G	0004325	molecular_function	ferrochelatase activity
G	0004601	molecular_function	peroxidase activity
G	0005829	cellular_component	cytosol
G	0016491	molecular_function	oxidoreductase activity
G	0016829	molecular_function	lyase activity
G	0020037	molecular_function	heme binding
G	0030313	cellular_component	cell envelope
G	0033212	biological_process	iron import into cell
G	0046872	molecular_function	metal ion binding
G	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM B 501

Chain	Residue
B	ASN245
B	THR357
B	ARG358
B	PRO359
B	ARG369
B	PHE390
B	PHE401
B	GLN405
B	LEU414
B	OXY503
B	HOH606
B	GLN249
B	HOH994
B	HOH1046
B	VAL250
B	GLY252
B	THR253
B	ARG254
B	ILE294
B	MET296
B	HIS353

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL B 502

Chain	Residue
A	ARG137
A	ASP138
A	HOH962
A	HOH981
B	GLU302
B	LEU304
B	LEU306
B	GLN309
B	HOH730
B	HOH975

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OXY B 503

Chain	Residue
B	ASP251
B	ARG369
B	HEM501

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT B 504

Chain	Residue
B	ARG254
B	GLU260
B	ARG266

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 505

Chain	Residue
B	GLY235
B	ALA236
B	THR237
B	HOH772
B	HOH849
B	HOH932
B	HOH944

---

site_id	AC6
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM A 501

Chain	Residue
A	ASN245
A	GLN249
A	VAL250
A	GLY252
A	THR253
A	ARG254
A	ILE294
A	MET296
A	HIS353
A	THR357
A	ARG358
A	PRO359
A	ARG369
A	PHE390
A	PHE401
A	VAL404
A	GLN405
A	LEU414
A	OXY503
A	HOH614
A	HOH701
A	HOH874

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 502

Chain	Residue
A	ARG254
A	ASN255
A	GLU260
A	ARG266
A	PRO359
A	HOH692
A	HOH874

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OXY A 503

Chain	Residue
A	ASP251
A	ARG369
A	HEM501

---

site_id	AC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	GLU302
A	LEU304
A	LEU306
A	GLN309
A	HOH660
A	HOH721
B	ARG137
B	ASP138
B	HOH854

---

site_id	BC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM E 501

Chain	Residue
E	PHE401
E	VAL404
E	GLN405
E	LEU408
E	OXY504
E	HOH668
E	HOH669
E	HOH683
E	ASN245
E	GLN249
E	VAL250
E	GLY252
E	THR253
E	ARG254
E	ILE294
E	MET296
E	HIS353
E	THR357
E	ARG358
E	PRO359
E	ARG369
E	PHE390

---

site_id	BC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL E 502

Chain	Residue
E	ARG137
E	ASP138
E	HOH722
E	HOH741
E	HOH949
E	HOH950
G	GLU302
G	LEU304
G	LEU306
G	GLN309

---

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL E 503

Chain	Residue
E	ARG254
E	ASN255
E	LYS257
E	GLU260
E	ARG266
E	HOH668
E	HOH761
E	HOH984

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OXY E 504

Chain	Residue
E	ASP251
E	ARG369
E	HEM501

---

site_id	BC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL E 505

Chain	Residue
E	GLU302
E	LEU304
E	LEU306
E	GLN309
E	HOH625
E	HOH820
E	HOH973
G	ARG137
G	ASP138
G	HOH655

---

site_id	BC6
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM G 501

Chain	Residue
G	ASN245
G	GLN249
G	VAL250
G	GLY252
G	THR253
G	ARG254
G	ILE294
G	MET296
G	HIS353
G	THR357
G	ARG358
G	PRO359
G	ARG369
G	PHE390
G	PHE401
G	VAL404
G	GLN405
G	OXY502
G	HOH637
G	HOH958
G	HOH1024

---

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OXY G 502

Chain	Residue
G	ASP251
G	ARG369
G	HEM501

---

site_id	BC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL G 503

Chain	Residue
G	PRO234
G	GLY235
G	ALA236
G	THR237
G	PRO240
G	HOH692
G	HOH883
G	HOH886
G	HOH906

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