4GS9
Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains in complex with an inactive benzoxadiazole antagonist
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 0XB A 401 |
| Chain | Residue |
| A | SER246 |
| A | MET309 |
| A | THR321 |
| A | ASN341 |
| A | HIS248 |
| A | MET252 |
| A | ALA277 |
| A | TYR281 |
| A | MET289 |
| A | SER292 |
| A | HIS293 |
| A | TYR307 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PE8 A 402 |
| Chain | Residue |
| A | TYR278 |
| A | THR290 |
| A | HIS293 |
| A | GLN294 |
| A | THR298 |
| B | TYR386 |
| B | GLU390 |
| B | LYS394 |
| B | GLU398 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 43 |
| Details | Domain: {"description":"PAC"} |
| Chain | Residue | Details |
