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4GP1

Crystal structure of ISOPRENOID SYNTHASE A3MSH1 (TARGET EFI-501992) from pyrobaculum calidifontis complexed with DMAPP

Functional Information from GO Data
ChainGOidnamespacecontents
A0004311molecular_functiongeranylgeranyl diphosphate synthase activity
A0004659molecular_functionprenyltransferase activity
A0008299biological_processisoprenoid biosynthetic process
A0016740molecular_functiontransferase activity
A0033386biological_processgeranylgeranyl diphosphate biosynthetic process
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CL A 401
ChainResidue
AGLN63
ATRP64
AARG65

site_idAC2
Number of Residues12
DetailsBINDING SITE FOR RESIDUE DMA A 402
ChainResidue
APHE221
AHOH517
AHOH518
AHOH566
AHOH573
AHOH768
AGLY45
ALYS46
ALEU48
AARG49
AHIS78
AARG95

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE PG4 A 403
ChainResidue
AGLU139
ALYS194
AARG204
AGLU208
ATRP211
AHOH792

Functional Information from PROSITE/UniProt
site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LIyDDii..DrgdvRRG
ChainResidueDetails
ALEU82-GLY96

246704

PDB entries from 2025-12-24

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