Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4GN3

OBody AM1L10 bound to hen egg-white lysozyme

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0016231	molecular_function	beta-N-acetylglucosaminidase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium
A	0042802	molecular_function	identical protein binding
A	0050829	biological_process	defense response to Gram-negative bacterium
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
B	0003676	molecular_function	nucleic acid binding
C	0003796	molecular_function	lysozyme activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0016231	molecular_function	beta-N-acetylglucosaminidase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0016998	biological_process	cell wall macromolecule catabolic process
C	0031640	biological_process	killing of cells of another organism
C	0042742	biological_process	defense response to bacterium
C	0042802	molecular_function	identical protein binding
C	0050829	biological_process	defense response to Gram-negative bacterium
C	0050830	biological_process	defense response to Gram-positive bacterium
C	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
D	0003676	molecular_function	nucleic acid binding
E	0003796	molecular_function	lysozyme activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005737	cellular_component	cytoplasm
E	0005783	cellular_component	endoplasmic reticulum
E	0016231	molecular_function	beta-N-acetylglucosaminidase activity
E	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
E	0016998	biological_process	cell wall macromolecule catabolic process
E	0031640	biological_process	killing of cells of another organism
E	0042742	biological_process	defense response to bacterium
E	0042802	molecular_function	identical protein binding
E	0050829	biological_process	defense response to Gram-negative bacterium
E	0050830	biological_process	defense response to Gram-positive bacterium
E	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
F	0003676	molecular_function	nucleic acid binding
G	0003796	molecular_function	lysozyme activity
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005615	cellular_component	extracellular space
G	0005737	cellular_component	cytoplasm
G	0005783	cellular_component	endoplasmic reticulum
G	0016231	molecular_function	beta-N-acetylglucosaminidase activity
G	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
G	0016998	biological_process	cell wall macromolecule catabolic process
G	0031640	biological_process	killing of cells of another organism
G	0042742	biological_process	defense response to bacterium
G	0042802	molecular_function	identical protein binding
G	0050829	biological_process	defense response to Gram-negative bacterium
G	0050830	biological_process	defense response to Gram-positive bacterium
G	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
H	0003676	molecular_function	nucleic acid binding
I	0003796	molecular_function	lysozyme activity
I	0005515	molecular_function	protein binding
I	0005576	cellular_component	extracellular region
I	0005615	cellular_component	extracellular space
I	0005737	cellular_component	cytoplasm
I	0005783	cellular_component	endoplasmic reticulum
I	0016231	molecular_function	beta-N-acetylglucosaminidase activity
I	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
I	0016998	biological_process	cell wall macromolecule catabolic process
I	0031640	biological_process	killing of cells of another organism
I	0042742	biological_process	defense response to bacterium
I	0042802	molecular_function	identical protein binding
I	0050829	biological_process	defense response to Gram-negative bacterium
I	0050830	biological_process	defense response to Gram-positive bacterium
I	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
J	0003676	molecular_function	nucleic acid binding
K	0003796	molecular_function	lysozyme activity
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005615	cellular_component	extracellular space
K	0005737	cellular_component	cytoplasm
K	0005783	cellular_component	endoplasmic reticulum
K	0016231	molecular_function	beta-N-acetylglucosaminidase activity
K	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
K	0016998	biological_process	cell wall macromolecule catabolic process
K	0031640	biological_process	killing of cells of another organism
K	0042742	biological_process	defense response to bacterium
K	0042802	molecular_function	identical protein binding
K	0050829	biological_process	defense response to Gram-negative bacterium
K	0050830	biological_process	defense response to Gram-positive bacterium
K	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
L	0003676	molecular_function	nucleic acid binding
M	0003796	molecular_function	lysozyme activity
M	0005515	molecular_function	protein binding
M	0005576	cellular_component	extracellular region
M	0005615	cellular_component	extracellular space
M	0005737	cellular_component	cytoplasm
M	0005783	cellular_component	endoplasmic reticulum
M	0016231	molecular_function	beta-N-acetylglucosaminidase activity
M	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
M	0016998	biological_process	cell wall macromolecule catabolic process
M	0031640	biological_process	killing of cells of another organism
M	0042742	biological_process	defense response to bacterium
M	0042802	molecular_function	identical protein binding
M	0050829	biological_process	defense response to Gram-negative bacterium
M	0050830	biological_process	defense response to Gram-positive bacterium
M	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
N	0003676	molecular_function	nucleic acid binding
O	0003796	molecular_function	lysozyme activity
O	0005515	molecular_function	protein binding
O	0005576	cellular_component	extracellular region
O	0005615	cellular_component	extracellular space
O	0005737	cellular_component	cytoplasm
O	0005783	cellular_component	endoplasmic reticulum
O	0016231	molecular_function	beta-N-acetylglucosaminidase activity
O	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
O	0016998	biological_process	cell wall macromolecule catabolic process
O	0031640	biological_process	killing of cells of another organism
O	0042742	biological_process	defense response to bacterium
O	0042802	molecular_function	identical protein binding
O	0050829	biological_process	defense response to Gram-negative bacterium
O	0050830	biological_process	defense response to Gram-positive bacterium
O	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
P	0003676	molecular_function	nucleic acid binding
Q	0003796	molecular_function	lysozyme activity
Q	0005515	molecular_function	protein binding
Q	0005576	cellular_component	extracellular region
Q	0005615	cellular_component	extracellular space
Q	0005737	cellular_component	cytoplasm
Q	0005783	cellular_component	endoplasmic reticulum
Q	0016231	molecular_function	beta-N-acetylglucosaminidase activity
Q	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
Q	0016998	biological_process	cell wall macromolecule catabolic process
Q	0031640	biological_process	killing of cells of another organism
Q	0042742	biological_process	defense response to bacterium
Q	0042802	molecular_function	identical protein binding
Q	0050829	biological_process	defense response to Gram-negative bacterium
Q	0050830	biological_process	defense response to Gram-positive bacterium
Q	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
R	0003676	molecular_function	nucleic acid binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 201

Chain	Residue
A	PHE3
A	ARG14
A	HIS15
A	ASP87
A	ILE88
A	HOH354
A	HOH355

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 202

Chain	Residue
A	ARG45
A	HOH350
A	HOH463
B	TRP8
B	GLU11
B	HOH429
B	HOH460
A	THR43
A	ASN44

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EPE B 201

Chain	Residue
B	HIS7
B	LEU16
B	HOH355
B	HOH366
B	HOH371
B	HOH436
B	HOH456
E	ARG5
E	ALA122
E	TRP123

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL C 201

Chain	Residue
C	PHE3
C	ALA11
C	ARG14
C	HIS15
C	SER86
C	ASP87
C	ILE88
C	HOH416

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 202

Chain	Residue
C	ASN44
C	ARG45
C	HOH351
C	HOH460
C	HOH461
L	TRP8
L	GLU11

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EPE D 201

Chain	Residue
D	HIS7
D	LEU16
D	THR19
D	HOH378
O	ARG5
O	TRP123
O	HOH384

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL D 202

Chain	Residue
D	ALA10
D	ILE12
D	THR13
D	HOH305
D	HOH399
D	HOH424
K	THR47

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 203

Chain	Residue
D	TRP8
D	ALA10
D	GLU11
D	HOH343
K	ARG45
K	HOH450

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL E 201

Chain	Residue
E	THR43
E	ASN44
E	ARG45
E	HOH307
E	HOH446
P	TRP8
P	GLU11
P	HOH367

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL E 202

Chain	Residue
E	LYS1
E	PHE3
E	ALA11
E	ARG14
E	HIS15
E	SER86
E	ASP87
E	ILE88

site_id	BC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EPE F 201

Chain	Residue
F	HIS7
F	LEU16
F	HOH318
F	HOH337
F	HOH400
F	HOH403
G	ARG5
G	ALA122
G	TRP123

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL G 201

Chain	Residue
G	LYS1
G	PHE3
G	ARG14
G	HIS15
G	SER86
G	ASP87
G	ILE88
G	HOH418

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL G 202

Chain	Residue
R	TRP8
R	GLU11
G	THR43
G	ASN44
G	ARG45
G	HOH309
G	HOH368

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE H 201

Chain	Residue
H	HIS7
H	LEU16
H	HOH336
H	HOH350
H	HOH365
H	HOH381
M	ARG5
M	TRP123

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL I 201

Chain	Residue
I	ASN44
I	ARG45
I	HOH411
I	HOH436
I	HOH441
N	GLU11

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL I 202

Chain	Residue
I	PHE3
I	ALA11
I	ARG14
I	HIS15
I	ASP87
I	ILE88
I	HOH339

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE J 201

Chain	Residue
C	ARG5
C	TRP123
C	HOH434
J	HIS7
J	LEU16
J	HOH331
J	HOH385
J	HOH394

site_id	BC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL K 201

Chain	Residue
K	PHE3
K	ARG14
K	HIS15
K	ASP87
K	ILE88
K	HOH339
K	HOH390

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EPE L 201

Chain	Residue
A	ARG5
L	HIS7
L	HOH360
L	HOH405
L	HOH406
L	HOH452

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL L 202

Chain	Residue
A	GLU7
L	HIS17
L	HOH445

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL M 201

Chain	Residue
M	ALA11
M	ARG14
M	HIS15
M	ASP87
M	ILE88
M	HOH356
M	HOH420

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL M 202

Chain	Residue
M	ASN44
M	ARG45
M	HOH428

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EPE N 201

Chain	Residue
N	HIS7
N	THR19
N	HOH393
Q	ARG5
Q	TRP123

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL O 201

Chain	Residue
O	ALA11
O	ARG14
O	HIS15
O	SER86
O	ASP87
O	ILE88

site_id	CC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EPE P 201

Chain	Residue
I	ARG5
I	ALA122
I	TRP123
P	HIS7
P	LEU16
P	HOH397
P	HOH399
P	HOH402

site_id	CC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL Q 201

Chain	Residue
Q	ALA11
Q	ARG14
Q	HIS15
Q	SER86
Q	ASP87
Q	ILE88
Q	HOH426

site_id	CC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EPE R 201

Chain	Residue
K	ARG5
K	TRP123
R	HIS7
R	LEU16
R	THR19
R	HOH365

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
A	CYS76-CYS94

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	ACT_SITE:

Chain	Residue	Details
A	GLU35
I	ASP52
K	GLU35
K	ASP52
M	GLU35
M	ASP52
O	GLU35
O	ASP52
Q	GLU35
Q	ASP52
A	ASP52
C	GLU35
C	ASP52
E	GLU35
E	ASP52
G	GLU35
G	ASP52
I	GLU35

site_id	SWS_FT_FI2
Number of Residues	9
Details	BINDING:

Chain	Residue	Details
A	ASP101
C	ASP101
E	ASP101
G	ASP101
I	ASP101
K	ASP101
M	ASP101
O	ASP101
Q	ASP101

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
A	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	ASN46
A	ASP48
A	SER50
A	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
A	ASN59

site_id	MCSA2
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
C	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
C	ASN46
C	ASP48
C	SER50
C	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
C	ASN59

site_id	MCSA3
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
E	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
E	ASN46
E	ASP48
E	SER50
E	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
E	ASN59

site_id	MCSA4
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
G	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
G	ASN46
G	ASP48
G	SER50
G	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
G	ASN59

site_id	MCSA5
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
I	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
I	ASN46
I	ASP48
I	SER50
I	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
I	ASN59

site_id	MCSA6
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
K	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
K	ASN46
K	ASP48
K	SER50
K	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
K	ASN59

site_id	MCSA7
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
M	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
M	ASN46
M	ASP48
M	SER50
M	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
M	ASN59

site_id	MCSA8
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
O	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
O	ASN46
O	ASP48
O	SER50
O	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
O	ASN59

site_id	MCSA9
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
Q	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
Q	ASN46
Q	ASP48
Q	SER50
Q	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
Q	ASN59

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)