Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0008927 | molecular_function | mannonate dehydratase activity |
| A | 0009063 | biological_process | amino acid catabolic process |
| A | 0016052 | biological_process | carbohydrate catabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0008927 | molecular_function | mannonate dehydratase activity |
| C | 0009063 | biological_process | amino acid catabolic process |
| C | 0016052 | biological_process | carbohydrate catabolic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 501 |
| Chain | Residue |
| A | ASP234 |
| A | GLU260 |
| A | GLU286 |
| A | ARG307 |
| A | CO3504 |
| A | HOH601 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 502 |
| Chain | Residue |
| A | ALA106 |
| C | VAL105 |
| C | CL502 |
| A | GLY102 |
| A | GLY103 |
| A | VAL105 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 503 |
| Chain | Residue |
| A | ASN61 |
| A | HIS236 |
| A | GLU286 |
| A | HIS336 |
| A | ALA338 |
| A | ASP340 |
| A | TRP426 |
| A | CO3504 |
| A | HOH845 |
| C | TYR99 |
| C | TRP100 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CO3 A 504 |
| Chain | Residue |
| A | ARG171 |
| A | TYR183 |
| A | ASP234 |
| A | GLU260 |
| A | GLU286 |
| A | ARG307 |
| A | GLU363 |
| A | MG501 |
| A | GOL503 |
| A | HOH602 |
| A | HOH845 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 501 |
| Chain | Residue |
| C | ASP234 |
| C | GLU260 |
| C | GLU286 |
| C | ARG307 |
| C | CS2503 |
| C | HOH601 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL C 502 |
| Chain | Residue |
| A | PRO104 |
| A | VAL105 |
| A | CL502 |
| C | GLY102 |
| C | GLY103 |
| C | VAL105 |
| C | ALA106 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE CS2 C 503 |
| Chain | Residue |
| A | TYR99 |
| A | TRP100 |
| C | ASN61 |
| C | ARG171 |
| C | TYR183 |
| C | ASP234 |
| C | HIS236 |
| C | GLU260 |
| C | GLU286 |
| C | ARG307 |
| C | HIS336 |
| C | ALA338 |
| C | ASP340 |
| C | GLU363 |
| C | LEU413 |
| C | TRP426 |
| C | MG501 |
| C | HOH602 |
| C | HOH605 |
| C | HOH606 |
Functional Information from PROSITE/UniProt
| site_id | PS00908 |
| Number of Residues | 26 |
| Details | MR_MLE_1 Mandelate racemase / muconate lactonizing enzyme family signature 1. AlAAVDmALwDIkGKvaglPVyqLLG |
| Chain | Residue | Details |
| A | ALA109-GLY134 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR183 | |
| A | HIS236 | |
| C | TYR183 | |
| C | HIS236 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: |
| Chain | Residue | Details |
| C | ASN61 | |
| C | GLU286 | |
| C | ARG307 | |
| C | HIS336 | |
| C | ASP340 | |
| C | GLU363 | |
| A | ASN61 | |
| A | GLU286 | |
| A | ARG307 | |
| A | HIS336 | |
| A | ASP340 | |
| A | GLU363 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| C | HIS146 | |
| A | HIS146 | |
| Chain | Residue | Details |
| C | ASP234 | |
| C | GLU260 | |
| A | GLU260 | |
| A | ASP234 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Important for activity and substrate specificity; Ala is observed in family members with high D-mannonate dehydratase activity that have no activity with D-gluconate => ECO:0000250 |
| Chain | Residue | Details |
| A | ALA338 | |
| C | ALA338 | |
