Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003911 | molecular_function | DNA ligase (NAD+) activity |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 601 |
| Chain | Residue |
| A | CYS408 |
| A | CYS411 |
| A | CYS426 |
| A | CYS432 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 602 |
| Chain | Residue |
| A | ARG74 |
| A | ARG510 |
| A | HOH850 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 0XS A 603 |
| Chain | Residue |
| A | LEU114 |
| A | LYS115 |
| A | LEU116 |
| A | GLU173 |
| A | TYR225 |
| A | VAL288 |
| A | LYS290 |
| A | PRO307 |
| A | TRP309 |
| A | HOH788 |
| A | HOH849 |
| A | LEU80 |
| A | GLU113 |
Functional Information from PROSITE/UniProt
| site_id | PS01055 |
| Number of Residues | 30 |
| Details | DNA_LIGASE_N1 NAD-dependent DNA ligase signature 1. KLDGLAvsilYenGvLvsaaTRGDGttGED |
| Chain | Residue | Details |
| A | LYS115-ASP144 | |
| site_id | PS01056 |
| Number of Residues | 16 |
| Details | DNA_LIGASE_N2 NAD-dependent DNA ligase signature 2. VGRTGaITpVarLePV |
| Chain | Residue | Details |
| A | VAL331-VAL346 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | Region: {"description":"Interaction with target DNA","evidences":[{"source":"PubMed","id":"17466627","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"N6-AMP-lysine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_01588","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11781321","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01588","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01588","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17466627","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01588","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17466627","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with target DNA","evidences":[{"source":"PubMed","id":"17466627","evidenceCode":"ECO:0000305"}]} |
