4GLT

Crystal structure of glutathione s-transferase MFLA_2116 (target EFI-507160) from methylobacillus flagellatus kt with gsh bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0005737	cellular_component	cytoplasm
A	0006749	biological_process	glutathione metabolic process
A	0016740	molecular_function	transferase activity
A	0019852	biological_process	L-ascorbic acid metabolic process
A	0045174	molecular_function	glutathione dehydrogenase (ascorbate) activity
A	0098869	biological_process	cellular oxidant detoxification
B	0004364	molecular_function	glutathione transferase activity
B	0005737	cellular_component	cytoplasm
B	0006749	biological_process	glutathione metabolic process
B	0016740	molecular_function	transferase activity
B	0019852	biological_process	L-ascorbic acid metabolic process
B	0045174	molecular_function	glutathione dehydrogenase (ascorbate) activity
B	0098869	biological_process	cellular oxidant detoxification
C	0004364	molecular_function	glutathione transferase activity
C	0005737	cellular_component	cytoplasm
C	0006749	biological_process	glutathione metabolic process
C	0016740	molecular_function	transferase activity
C	0019852	biological_process	L-ascorbic acid metabolic process
C	0045174	molecular_function	glutathione dehydrogenase (ascorbate) activity
C	0098869	biological_process	cellular oxidant detoxification
D	0004364	molecular_function	glutathione transferase activity
D	0005737	cellular_component	cytoplasm
D	0006749	biological_process	glutathione metabolic process
D	0016740	molecular_function	transferase activity
D	0019852	biological_process	L-ascorbic acid metabolic process
D	0045174	molecular_function	glutathione dehydrogenase (ascorbate) activity
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GSH A 301

Chain	Residue
A	THR8
A	SER63
A	TYR165
A	ARG169
A	SER9
A	PRO10
A	TYR11
A	LEU33
A	LYS48
A	ILE49
A	PRO50
A	ASP62

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GSH B 301

Chain	Residue
A	LYS125
A	LYS129
B	SER9
B	TYR11
B	LYS48
B	ILE49
B	PRO50
B	ASP62
B	SER63
B	HOH403

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site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GSH C 301

Chain	Residue
C	SER9
C	TYR11
C	GLY47
C	LYS48
C	ILE49
C	PRO50
C	ASP62
C	SER63
C	HOH401
C	HOH415
C	HOH417
D	LYS129

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site_id	AC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GSH D 301

Chain	Residue
C	LYS125
C	LYS129
D	SER9
D	GLY47
D	LYS48
D	ILE49
D	PRO50
D	ASP62
D	SER63
D	HOH406
D	HOH407
D	HOH417
D	HOH418

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