Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004601 | molecular_function | peroxidase activity |
A | 0006979 | biological_process | response to oxidative stress |
A | 0020037 | molecular_function | heme binding |
A | 0034599 | biological_process | cellular response to oxidative stress |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005739 | cellular_component | mitochondrion |
B | 0005758 | cellular_component | mitochondrial intermembrane space |
B | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
B | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
B | 0009055 | molecular_function | electron transfer activity |
B | 0020037 | molecular_function | heme binding |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE HEM A 401 |
Chain | Residue |
A | PRO60 |
A | HIS198 |
A | PHE201 |
A | SER202 |
A | TRP208 |
A | SER252 |
A | HOH501 |
A | HOH512 |
A | HOH561 |
A | HOH663 |
A | TRP67 |
A | PRO162 |
A | LEU188 |
A | ALA191 |
A | HIS192 |
A | GLY195 |
A | GLU196 |
A | CYS197 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE K A 402 |
Chain | Residue |
A | THR193 |
A | THR209 |
A | ASP211 |
A | GLY214 |
A | ASP216 |
A | SER218 |
A | HOH569 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 403 |
Chain | Residue |
A | GLU69 |
A | SER72 |
A | GLY80 |
A | SER81 |
A | SER86 |
A | GLU92 |
site_id | AC4 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE HEC B 201 |
Chain | Residue |
B | ARG24 |
B | ALA25 |
B | CYS28 |
B | HIS29 |
B | VAL39 |
B | ILE46 |
B | SER51 |
B | GLY52 |
B | VAL54 |
B | TYR59 |
B | SER60 |
B | ASN63 |
B | TRP70 |
B | LEU75 |
B | LEU79 |
B | THR89 |
B | LYS90 |
B | MET91 |
B | SER92 |
B | PHE93 |
B | ILE96 |
B | HOH302 |
Functional Information from PROSITE/UniProt
site_id | PS00436 |
Number of Residues | 12 |
Details | PEROXIDASE_2 Peroxidases active site signature. GPslIRLaWHEA |
Chain | Residue | Details |
A | GLY59-ALA70 | |