4GE8
OYE1-W116I complexed with (s)-Carvone
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | HOH836 |
| A | HOH900 |
| A | HOH918 |
| A | HOH919 |
| A | HOH937 |
| A | HOH938 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| Chain | Residue |
| A | ASP83 |
| A | ASN126 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 403 |
| Chain | Residue |
| A | LYS368 |
| A | HOH916 |
| A | HOH950 |
| A | LYS4 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 404 |
| Chain | Residue |
| A | ALA145 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 405 |
| Chain | Residue |
| A | TYR375 |
| A | 1PE409 |
| A | HOH838 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 406 |
| Chain | Residue |
| A | ALA10 |
| A | 1PE410 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 407 |
| Chain | Residue |
| A | TRP52 |
| A | 1PE408 |
| A | HOH826 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 1PE A 408 |
| Chain | Residue |
| A | TRP52 |
| A | ASP358 |
| A | ALA379 |
| A | GLU389 |
| A | NA407 |
| A | HOH962 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 1PE A 409 |
| Chain | Residue |
| A | TYR82 |
| A | PHE123 |
| A | PHE296 |
| A | NA405 |
| A | HOH752 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 1PE A 410 |
| Chain | Residue |
| A | PRO8 |
| A | GLN9 |
| A | ALA10 |
| A | HIS43 |
| A | ASP83 |
| A | ASN84 |
| A | ARG334 |
| A | LYS362 |
| A | GLY363 |
| A | NA406 |
| A | HOH652 |
| A | HOH858 |
| site_id | BC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FMN A 411 |
| Chain | Residue |
| A | PRO34 |
| A | PRO35 |
| A | LEU36 |
| A | THR37 |
| A | GLY72 |
| A | GLN114 |
| A | HIS191 |
| A | ASN194 |
| A | ARG243 |
| A | GLY324 |
| A | ASN325 |
| A | GLY347 |
| A | ARG348 |
| A | PHE374 |
| A | 0WU414 |
| A | HOH503 |
| A | HOH504 |
| A | HOH506 |
| A | HOH515 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA A 412 |
| Chain | Residue |
| A | 1PE413 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 1PE A 413 |
| Chain | Residue |
| A | ASP370 |
| A | HIS380 |
| A | ASP384 |
| A | NA412 |
| A | HOH785 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 0WU A 414 |
| Chain | Residue |
| A | THR37 |
| A | TYR82 |
| A | ILE116 |
| A | HIS191 |
| A | ASN194 |
| A | TYR196 |
| A | TYR375 |
| A | FMN411 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000305|PubMed:9830020 |
| Chain | Residue | Details |
| A | TYR196 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11668181, ECO:0000269|PubMed:7881908, ECO:0000269|PubMed:9830019 |
| Chain | Residue | Details |
| A | THR37 | |
| A | GLN114 | |
| A | ARG243 | |
| A | ARG348 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11668181, ECO:0000269|PubMed:7881908 |
| Chain | Residue | Details |
| A | HIS191 | |
| A | ASN194 | |
| A | TYR375 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 319 |
| Chain | Residue | Details |
| A | THR37 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS191 | electrostatic stabiliser, hydrogen bond donor |
| A | ASN194 | electrostatic stabiliser, hydrogen bond donor |
| A | TYR196 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN251 | hydrogen bond donor, increase acidity |
