4GE0

Schizosaccharomyces pombe DJ-1 T114P mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0016829	molecular_function	lyase activity
A	0019172	molecular_function	glyoxalase III activity
A	0019249	biological_process	lactate biosynthetic process
A	0061727	biological_process	methylglyoxal catabolic process to lactate
A	1903189	biological_process	glyoxal metabolic process
A	1990748	biological_process	cellular detoxification
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006979	biological_process	response to oxidative stress
B	0016829	molecular_function	lyase activity
B	0019172	molecular_function	glyoxalase III activity
B	0019249	biological_process	lactate biosynthetic process
B	0061727	biological_process	methylglyoxal catabolic process to lactate
B	1903189	biological_process	glyoxal metabolic process
B	1990748	biological_process	cellular detoxification
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006979	biological_process	response to oxidative stress
C	0016829	molecular_function	lyase activity
C	0019172	molecular_function	glyoxalase III activity
C	0019249	biological_process	lactate biosynthetic process
C	0061727	biological_process	methylglyoxal catabolic process to lactate
C	1903189	biological_process	glyoxal metabolic process
C	1990748	biological_process	cellular detoxification
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0006979	biological_process	response to oxidative stress
D	0016829	molecular_function	lyase activity
D	0019172	molecular_function	glyoxalase III activity
D	0019249	biological_process	lactate biosynthetic process
D	0061727	biological_process	methylglyoxal catabolic process to lactate
D	1903189	biological_process	glyoxal metabolic process
D	1990748	biological_process	cellular detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 201

Chain	Residue
B	GLY11
B	LYS45
B	MET46
B	SER47
B	ASP49
B	HOH336
B	HOH352

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO C 201

Chain	Residue
C	SER18
C	MET46
C	HOH509
D	SER18
D	HOH312
C	GLU14
C	PHE17

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 202

Chain	Residue
B	HOH503
C	HOH419
D	HOH244
D	HOH246

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 203

Chain	Residue
A	HOH437
C	HOH531
C	HOH540
C	HOH589
C	HOH590

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {"evidences":[{"source":"PubMed","id":"24758716","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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