4GDE
Crystal structure of NADPH-reduced Aspergillus fumigatus UDP-galactopyranose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0071555 | biological_process | cell wall organization |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0071555 | biological_process | cell wall organization |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0071555 | biological_process | cell wall organization |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0008767 | molecular_function | UDP-galactopyranose mutase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FDA A 601 |
| Chain | Residue |
| A | GLY14 |
| A | VAL60 |
| A | GLY62 |
| A | HIS63 |
| A | VAL64 |
| A | GLY240 |
| A | VAL242 |
| A | MET269 |
| A | GLU373 |
| A | GLY418 |
| A | GLY446 |
| A | GLY16 |
| A | ARG447 |
| A | GLY456 |
| A | ASN457 |
| A | GLN458 |
| A | SER461 |
| A | HOH703 |
| A | HOH736 |
| A | HOH737 |
| A | HOH792 |
| A | HOH806 |
| A | PRO17 |
| A | THR18 |
| A | ASP38 |
| A | SER39 |
| A | GLY45 |
| A | LEU46 |
| A | ALA47 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 602 |
| Chain | Residue |
| A | THR137 |
| A | LYS138 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 603 |
| Chain | Residue |
| A | ASN40 |
| A | ASP50 |
| A | ARG413 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 604 |
| Chain | Residue |
| A | GLU308 |
| A | ARG309 |
| A | LYS402 |
| A | HOH823 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 605 |
| Chain | Residue |
| A | LYS70 |
| A | ARG496 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 606 |
| Chain | Residue |
| A | LYS82 |
| A | GLU83 |
| site_id | AC7 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE FDA B 601 |
| Chain | Residue |
| B | GLY14 |
| B | GLY16 |
| B | PRO17 |
| B | THR18 |
| B | ASP38 |
| B | SER39 |
| B | GLY45 |
| B | LEU46 |
| B | ALA47 |
| B | VAL60 |
| B | GLY62 |
| B | HIS63 |
| B | VAL64 |
| B | GLY240 |
| B | VAL242 |
| B | MET269 |
| B | THR295 |
| B | GLU373 |
| B | GLY418 |
| B | GLY446 |
| B | ARG447 |
| B | GLY456 |
| B | ASN457 |
| B | GLN458 |
| B | SER461 |
| B | HOH704 |
| B | HOH728 |
| B | HOH729 |
| B | HOH763 |
| B | HOH764 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 602 |
| Chain | Residue |
| B | LYS70 |
| B | ARG496 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 603 |
| Chain | Residue |
| B | PRO114 |
| B | LYS115 |
| B | ASN383 |
| B | THR386 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 604 |
| Chain | Residue |
| B | PRO307 |
| B | GLU308 |
| B | ARG309 |
| B | LYS402 |
| B | HOH812 |
| site_id | BC2 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE FDA C 601 |
| Chain | Residue |
| C | THR295 |
| C | GLU373 |
| C | GLY418 |
| C | TYR419 |
| C | GLY446 |
| C | ARG447 |
| C | GLY456 |
| C | ASN457 |
| C | GLN458 |
| C | SER461 |
| C | HOH730 |
| C | HOH776 |
| C | GLY14 |
| C | GLY16 |
| C | PRO17 |
| C | THR18 |
| C | ASP38 |
| C | SER39 |
| C | GLY45 |
| C | LEU46 |
| C | ALA47 |
| C | VAL60 |
| C | GLY62 |
| C | HIS63 |
| C | VAL64 |
| C | GLY240 |
| C | VAL242 |
| C | MET269 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 602 |
| Chain | Residue |
| C | PRO114 |
| C | LYS115 |
| C | HOH740 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 603 |
| Chain | Residue |
| C | PRO307 |
| C | GLU308 |
| C | ARG309 |
| C | LYS402 |
| site_id | BC5 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE FDA D 601 |
| Chain | Residue |
| D | GLY14 |
| D | GLY16 |
| D | PRO17 |
| D | THR18 |
| D | ASP38 |
| D | SER39 |
| D | GLY45 |
| D | LEU46 |
| D | ALA47 |
| D | VAL60 |
| D | GLY62 |
| D | HIS63 |
| D | VAL64 |
| D | GLY240 |
| D | VAL242 |
| D | MET269 |
| D | THR295 |
| D | GLU373 |
| D | GLY418 |
| D | GLY446 |
| D | ARG447 |
| D | GLY456 |
| D | ASN457 |
| D | GLN458 |
| D | SER461 |
| D | HOH749 |
| D | HOH750 |
| D | HOH778 |
| D | HOH785 |
| D | HOH786 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 602 |
| Chain | Residue |
| D | THR152 |
| D | ARG160 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 603 |
| Chain | Residue |
| D | PRO307 |
| D | GLU308 |
| D | ARG309 |
| D | LYS402 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 604 |
| Chain | Residue |
| D | PRO114 |
| D | LYS115 |
| D | HOH743 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKA, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKK, ECO:0007744|PDB:3UKL, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UTE |
| Chain | Residue | Details |
| A | THR18 | |
| B | ASP38 | |
| B | LEU46 | |
| B | HIS63 | |
| B | VAL242 | |
| B | GLY456 | |
| B | GLN458 | |
| B | SER461 | |
| C | THR18 | |
| C | ASP38 | |
| C | LEU46 | |
| A | ASP38 | |
| C | HIS63 | |
| C | VAL242 | |
| C | GLY456 | |
| C | GLN458 | |
| C | SER461 | |
| D | THR18 | |
| D | ASP38 | |
| D | LEU46 | |
| D | HIS63 | |
| D | VAL242 | |
| A | LEU46 | |
| D | GLY456 | |
| D | GLN458 | |
| D | SER461 | |
| A | HIS63 | |
| A | VAL242 | |
| A | GLY456 | |
| A | GLN458 | |
| A | SER461 | |
| B | THR18 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKP |
| Chain | Residue | Details |
| A | GLY61 | |
| B | GLY61 | |
| C | GLY61 | |
| D | GLY61 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UKQ |
| Chain | Residue | Details |
| A | GLY62 | |
| B | GLY62 | |
| C | GLY62 | |
| D | GLY62 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23036087, ECO:0007744|PDB:5VWT |
| Chain | Residue | Details |
| A | HIS68 | |
| B | SER93 | |
| B | ASN203 | |
| B | TRP315 | |
| B | ARG447 | |
| B | HIS460 | |
| C | HIS68 | |
| C | ARG91 | |
| C | SER93 | |
| C | ASN203 | |
| C | TRP315 | |
| A | ARG91 | |
| C | ARG447 | |
| C | HIS460 | |
| D | HIS68 | |
| D | ARG91 | |
| D | SER93 | |
| D | ASN203 | |
| D | TRP315 | |
| D | ARG447 | |
| D | HIS460 | |
| A | SER93 | |
| A | ASN203 | |
| A | TRP315 | |
| A | ARG447 | |
| A | HIS460 | |
| B | HIS68 | |
| B | ARG91 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 32 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKP, ECO:0007744|PDB:3UKQ, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | TYR104 | |
| B | GLN107 | |
| B | ASN163 | |
| B | TRP167 | |
| B | ARG182 | |
| B | ASN207 | |
| B | TYR419 | |
| B | TYR453 | |
| C | TYR104 | |
| C | GLN107 | |
| C | ASN163 | |
| A | GLN107 | |
| C | TRP167 | |
| C | ARG182 | |
| C | ASN207 | |
| C | TYR419 | |
| C | TYR453 | |
| D | TYR104 | |
| D | GLN107 | |
| D | ASN163 | |
| D | TRP167 | |
| D | ARG182 | |
| A | ASN163 | |
| D | ASN207 | |
| D | TYR419 | |
| D | TYR453 | |
| A | TRP167 | |
| A | ARG182 | |
| A | ASN207 | |
| A | TYR419 | |
| A | TYR453 | |
| B | TYR104 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKP |
| Chain | Residue | Details |
| A | MET159 | |
| A | TYR162 | |
| B | MET159 | |
| B | TYR162 | |
| C | MET159 | |
| C | TYR162 | |
| D | MET159 | |
| D | TYR162 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UKQ, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | TYR317 | |
| B | TYR317 | |
| C | TYR317 | |
| D | TYR317 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22294687, ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKF, ECO:0007744|PDB:3UKH, ECO:0007744|PDB:3UTH |
| Chain | Residue | Details |
| A | ARG327 | |
| B | ARG327 | |
| C | ARG327 | |
| D | ARG327 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22334662, ECO:0007744|PDB:3UKH |
| Chain | Residue | Details |
| A | ASN457 | |
| B | ASN457 | |
| C | ASN457 | |
| D | ASN457 |
