4GDE

Crystal structure of NADPH-reduced Aspergillus fumigatus UDP-galactopyranose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008767	molecular_function	UDP-galactopyranose mutase activity
A	0016853	molecular_function	isomerase activity
A	0071555	biological_process	cell wall organization
B	0000166	molecular_function	nucleotide binding
B	0008767	molecular_function	UDP-galactopyranose mutase activity
B	0016853	molecular_function	isomerase activity
B	0071555	biological_process	cell wall organization
C	0000166	molecular_function	nucleotide binding
C	0008767	molecular_function	UDP-galactopyranose mutase activity
C	0016853	molecular_function	isomerase activity
C	0071555	biological_process	cell wall organization
D	0000166	molecular_function	nucleotide binding
D	0008767	molecular_function	UDP-galactopyranose mutase activity
D	0016853	molecular_function	isomerase activity
D	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	29
Details	BINDING SITE FOR RESIDUE FDA A 601

Chain	Residue
A	GLY14
A	VAL60
A	GLY62
A	HIS63
A	VAL64
A	GLY240
A	VAL242
A	MET269
A	GLU373
A	GLY418
A	GLY446
A	GLY16
A	ARG447
A	GLY456
A	ASN457
A	GLN458
A	SER461
A	HOH703
A	HOH736
A	HOH737
A	HOH792
A	HOH806
A	PRO17
A	THR18
A	ASP38
A	SER39
A	GLY45
A	LEU46
A	ALA47

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 602

Chain	Residue
A	THR137
A	LYS138

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 603

Chain	Residue
A	ASN40
A	ASP50
A	ARG413

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 604

Chain	Residue
A	GLU308
A	ARG309
A	LYS402
A	HOH823

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 605

Chain	Residue
A	LYS70
A	ARG496

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 606

Chain	Residue
A	LYS82
A	GLU83

---

site_id	AC7
Number of Residues	30
Details	BINDING SITE FOR RESIDUE FDA B 601

Chain	Residue
B	GLY14
B	GLY16
B	PRO17
B	THR18
B	ASP38
B	SER39
B	GLY45
B	LEU46
B	ALA47
B	VAL60
B	GLY62
B	HIS63
B	VAL64
B	GLY240
B	VAL242
B	MET269
B	THR295
B	GLU373
B	GLY418
B	GLY446
B	ARG447
B	GLY456
B	ASN457
B	GLN458
B	SER461
B	HOH704
B	HOH728
B	HOH729
B	HOH763
B	HOH764

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 602

Chain	Residue
B	LYS70
B	ARG496

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 603

Chain	Residue
B	PRO114
B	LYS115
B	ASN383
B	THR386

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 604

Chain	Residue
B	PRO307
B	GLU308
B	ARG309
B	LYS402
B	HOH812

---

site_id	BC2
Number of Residues	28
Details	BINDING SITE FOR RESIDUE FDA C 601

Chain	Residue
C	THR295
C	GLU373
C	GLY418
C	TYR419
C	GLY446
C	ARG447
C	GLY456
C	ASN457
C	GLN458
C	SER461
C	HOH730
C	HOH776
C	GLY14
C	GLY16
C	PRO17
C	THR18
C	ASP38
C	SER39
C	GLY45
C	LEU46
C	ALA47
C	VAL60
C	GLY62
C	HIS63
C	VAL64
C	GLY240
C	VAL242
C	MET269

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 602

Chain	Residue
C	PRO114
C	LYS115
C	HOH740

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 603

Chain	Residue
C	PRO307
C	GLU308
C	ARG309
C	LYS402

---

site_id	BC5
Number of Residues	30
Details	BINDING SITE FOR RESIDUE FDA D 601

Chain	Residue
D	GLY14
D	GLY16
D	PRO17
D	THR18
D	ASP38
D	SER39
D	GLY45
D	LEU46
D	ALA47
D	VAL60
D	GLY62
D	HIS63
D	VAL64
D	GLY240
D	VAL242
D	MET269
D	THR295
D	GLU373
D	GLY418
D	GLY446
D	ARG447
D	GLY456
D	ASN457
D	GLN458
D	SER461
D	HOH749
D	HOH750
D	HOH778
D	HOH785
D	HOH786

---

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 602

Chain	Residue
D	THR152
D	ARG160

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 603

Chain	Residue
D	PRO307
D	GLU308
D	ARG309
D	LYS402

---

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 604

Chain	Residue
D	PRO114
D	LYS115
D	HOH743

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23036087","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VWT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---