4GC7

Crystal structure of Dpo4 in complex with S-MC-dADP opposite dT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034061	molecular_function	DNA polymerase activity
B	0042276	biological_process	error-prone translesion synthesis
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 0OJ A 401

Chain	Residue
A	ASP7
A	HOH514
A	HOH515
C	DC14
D	DT4
D	DG5
A	TYR10
A	PHE11
A	TYR12
A	THR45
A	ARG51
A	LYS159
A	CA402
A	CA403

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 402

Chain	Residue
A	ASP7
A	GLU106
A	0OJ401
A	CA403

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 403

Chain	Residue
A	ASP7
A	PHE8
A	TYR10
A	ASP105
A	0OJ401
A	CA402

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 404

Chain	Residue
A	ALA181
A	ILE186
A	HOH505

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 405

Chain	Residue
A	ASP294
A	ILE295
B	GLU327
C	DG9
C	DA10
C	HOH102

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 406

Chain	Residue
A	GLU324
A	HOH501
B	GLU325
E	DG8

---

site_id	AC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 0OJ B 401

Chain	Residue
B	ASP7
B	PHE11
B	TYR12
B	ALA44
B	THR45
B	ARG51
B	ALA57
B	ASP105
B	LYS159
B	CA402
B	CA405
B	HOH501
B	HOH502
B	HOH514
B	HOH515
B	HOH516
E	DC14
F	DT4
F	DG5

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 402

Chain	Residue
B	ASP7
B	PHE8
B	ASP105
B	0OJ401
B	HOH515

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA B 403

Chain	Residue
B	ASP294
E	DA10

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA B 404

Chain	Residue
B	ALA181
B	ILE186

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 405

Chain	Residue
B	ASP7
B	ASP105
B	GLU106
B	0OJ401
E	DC14

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	368
Details	Domain: {"description":"UmuC"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Substrate discrimination"}

Chain

Residue

Details

---