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4GBY

The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to D-xylose

Functional Information from GO Data
ChainGOidnamespacecontents
A0005886cellular_componentplasma membrane
A0015293molecular_functionsymporter activity
A0015519molecular_functionD-xylose:proton symporter activity
A0015753biological_processD-xylose transmembrane transport
A0016020cellular_componentmembrane
A0022857molecular_functiontransmembrane transporter activity
A0055085biological_processtransmembrane transport
Functional Information from PROSITE/UniProt
site_idPS00216
Number of Residues18
DetailsSUGAR_TRANSPORT_1 Sugar transport proteins signature 1. AIMTVDKFGRKplqiigA
ChainResidueDetails
AALA332-ALA349

site_idPS00217
Number of Residues26
DetailsSUGAR_TRANSPORT_2 Sugar transport proteins signature 2. IgGIGvGLasmlspmYiaElapahiR
ChainResidueDetails
AILE135-ARG160

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues128
DetailsTOPO_DOM: Cytoplasmic
ChainResidueDetails
AMET1-TYR9
AASN80-ARG84
AILE151-LYS162
AGLU222-GLY276
ATHR335-PRO343
ACYS391-ALA407
APRO464-LEU491

site_idSWS_FT_FI2
Number of Residues22
DetailsTRANSMEM: Helical; Name=1
ChainResidueDetails
AILE10-SER32

site_idSWS_FT_FI3
Number of Residues92
DetailsTOPO_DOM: Periplasmic
ChainResidueDetails
AGLY33-GLY58
AGLU106-GLU128
APHE184-ARG200
AALA300-ASP312
ATHR365-GLY369
AMET429-GLY442

site_idSWS_FT_FI4
Number of Residues20
DetailsTRANSMEM: Helical; Name=2
ChainResidueDetails
APHE59-SER79

site_idSWS_FT_FI5
Number of Residues20
DetailsTRANSMEM: Helical; Name=3
ChainResidueDetails
AARG85-PRO105

site_idSWS_FT_FI6
Number of Residues21
DetailsTRANSMEM: Helical; Name=4
ChainResidueDetails
APHE129-TYR150

site_idSWS_FT_FI7
Number of Residues20
DetailsTRANSMEM: Helical; Name=5
ChainResidueDetails
ALEU163-TYR183

site_idSWS_FT_FI8
Number of Residues20
DetailsTRANSMEM: Helical; Name=6
ChainResidueDetails
ATYR201-PRO221

site_idSWS_FT_FI9
Number of Residues22
DetailsTRANSMEM: Helical; Name=7
ChainResidueDetails
AVAL277-TYR299

site_idSWS_FT_FI10
Number of Residues21
DetailsTRANSMEM: Helical; Name=8
ChainResidueDetails
AILE313-MET334

site_idSWS_FT_FI11
Number of Residues20
DetailsTRANSMEM: Helical; Name=9
ChainResidueDetails
ALEU344-TYR364

site_idSWS_FT_FI12
Number of Residues20
DetailsTRANSMEM: Helical; Name=10
ChainResidueDetails
AILE370-VAL390

site_idSWS_FT_FI13
Number of Residues20
DetailsTRANSMEM: Helical; Name=11
ChainResidueDetails
ALEU408-MET428

site_idSWS_FT_FI14
Number of Residues20
DetailsTRANSMEM: Helical; Name=12
ChainResidueDetails
APHE443-VAL463

site_idSWS_FT_FI15
Number of Residues5
DetailsBINDING: BINDING => ECO:0000269|PubMed:23075985, ECO:0007744|PDB:4GBY
ChainResidueDetails
AGLN168
AGLN288
AASN294
ATRP392
AGLN415

226707

PDB entries from 2024-10-30

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