Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4GA5

Crystal structure of AMP phosphorylase C-terminal deletion mutant in the apo-form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
A	0005829	cellular_component	cytosol
A	0006196	biological_process	AMP catabolic process
A	0006206	biological_process	pyrimidine nucleobase metabolic process
A	0006213	biological_process	pyrimidine nucleoside metabolic process
A	0009032	molecular_function	thymidine phosphorylase activity
A	0016208	molecular_function	AMP binding
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0042301	molecular_function	phosphate ion binding
A	0046125	biological_process	pyrimidine deoxyribonucleoside metabolic process
B	0003824	molecular_function	catalytic activity
B	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
B	0005829	cellular_component	cytosol
B	0006196	biological_process	AMP catabolic process
B	0006206	biological_process	pyrimidine nucleobase metabolic process
B	0006213	biological_process	pyrimidine nucleoside metabolic process
B	0009032	molecular_function	thymidine phosphorylase activity
B	0016208	molecular_function	AMP binding
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0042301	molecular_function	phosphate ion binding
B	0046125	biological_process	pyrimidine deoxyribonucleoside metabolic process
C	0003824	molecular_function	catalytic activity
C	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
C	0005829	cellular_component	cytosol
C	0006196	biological_process	AMP catabolic process
C	0006206	biological_process	pyrimidine nucleobase metabolic process
C	0006213	biological_process	pyrimidine nucleoside metabolic process
C	0009032	molecular_function	thymidine phosphorylase activity
C	0016208	molecular_function	AMP binding
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0042301	molecular_function	phosphate ion binding
C	0046125	biological_process	pyrimidine deoxyribonucleoside metabolic process
D	0003824	molecular_function	catalytic activity
D	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
D	0005829	cellular_component	cytosol
D	0006196	biological_process	AMP catabolic process
D	0006206	biological_process	pyrimidine nucleobase metabolic process
D	0006213	biological_process	pyrimidine nucleoside metabolic process
D	0009032	molecular_function	thymidine phosphorylase activity
D	0016208	molecular_function	AMP binding
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0016763	molecular_function	pentosyltransferase activity
D	0042301	molecular_function	phosphate ion binding
D	0046125	biological_process	pyrimidine deoxyribonucleoside metabolic process
E	0003824	molecular_function	catalytic activity
E	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
E	0005829	cellular_component	cytosol
E	0006196	biological_process	AMP catabolic process
E	0006206	biological_process	pyrimidine nucleobase metabolic process
E	0006213	biological_process	pyrimidine nucleoside metabolic process
E	0009032	molecular_function	thymidine phosphorylase activity
E	0016208	molecular_function	AMP binding
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
E	0016763	molecular_function	pentosyltransferase activity
E	0042301	molecular_function	phosphate ion binding
E	0046125	biological_process	pyrimidine deoxyribonucleoside metabolic process
F	0003824	molecular_function	catalytic activity
F	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
F	0005829	cellular_component	cytosol
F	0006196	biological_process	AMP catabolic process
F	0006206	biological_process	pyrimidine nucleobase metabolic process
F	0006213	biological_process	pyrimidine nucleoside metabolic process
F	0009032	molecular_function	thymidine phosphorylase activity
F	0016208	molecular_function	AMP binding
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity
F	0016763	molecular_function	pentosyltransferase activity
F	0042301	molecular_function	phosphate ion binding
F	0046125	biological_process	pyrimidine deoxyribonucleoside metabolic process
G	0003824	molecular_function	catalytic activity
G	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
G	0005829	cellular_component	cytosol
G	0006196	biological_process	AMP catabolic process
G	0006206	biological_process	pyrimidine nucleobase metabolic process
G	0006213	biological_process	pyrimidine nucleoside metabolic process
G	0009032	molecular_function	thymidine phosphorylase activity
G	0016208	molecular_function	AMP binding
G	0016740	molecular_function	transferase activity
G	0016757	molecular_function	glycosyltransferase activity
G	0016763	molecular_function	pentosyltransferase activity
G	0042301	molecular_function	phosphate ion binding
G	0046125	biological_process	pyrimidine deoxyribonucleoside metabolic process
H	0003824	molecular_function	catalytic activity
H	0004645	molecular_function	1,4-alpha-oligoglucan phosphorylase activity
H	0005829	cellular_component	cytosol
H	0006196	biological_process	AMP catabolic process
H	0006206	biological_process	pyrimidine nucleobase metabolic process
H	0006213	biological_process	pyrimidine nucleoside metabolic process
H	0009032	molecular_function	thymidine phosphorylase activity
H	0016208	molecular_function	AMP binding
H	0016740	molecular_function	transferase activity
H	0016757	molecular_function	glycosyltransferase activity
H	0016763	molecular_function	pentosyltransferase activity
H	0042301	molecular_function	phosphate ion binding
H	0046125	biological_process	pyrimidine deoxyribonucleoside metabolic process

Functional Information from PROSITE/UniProt

site_id	PS00430
Number of Residues	82
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mkakirildmfsgrytvlineedakeaklhpddlvkieagkkavygsvalsnlvgkgevgisrdvldlhnfseg.........................................ETVSVIPA

Chain	Residue	Details
B	MET1-ALA82

site_id	PS00647
Number of Residues	16
Details	THYMID_PHOSPHORYLASE Thymidine and pyrimidine-nucleoside phosphorylases signature. SSRAItsAAGTaDvVE

Chain	Residue	Details
B	SER193-GLU208

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"23659790","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23659790","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)