4G9A

Crystal structure of calcium2+-bound wild-type CD23 lectin domain

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 301

Chain	Residue
A	LYS276
A	HOH442
A	HOH463
A	HOH486
A	HOH487
B	HOH470
C	LEU226
C	GLU231
C	ILE233

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 302

Chain	Residue
A	GLU249
A	THR251
A	ASP270
A	HOH414
A	HOH434
C	HOH438

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 301

Chain	Residue
B	GLY196
B	GLN197
B	ARG284
B	LEU285
B	HOH458
B	HOH513

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 302

Chain	Residue
B	GLU249
B	THR251
B	ASP270
B	HOH407
B	HOH409
B	HOH412

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 301

Chain	Residue
C	GLU249
C	THR251
C	ASP270
C	HOH415
C	HOH474
C	HOH492

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 301

Chain	Residue
A	ARG267
A	HOH448
D	TRP245
D	HOH452

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA D 302

Chain	Residue
D	GLU249
D	ASP270
D	HOH468

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Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	24
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVmmrgsgr.....WNDAFCdrklgaWVC

Chain	Residue	Details
A	CYS259-CYS282

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:16765898

Chain	Residue	Details
A	GLU249
C	THR251
C	ASN269
C	ASP270
D	GLU249
D	THR251
D	ASN269
D	ASP270
A	THR251
A	ASN269
A	ASP270
B	GLU249
B	THR251
B	ASN269
B	ASP270
C	GLU249

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: O-linked (Xyl...) (chondroitin sulfate) serine => ECO:0000269|PubMed:37453717

Chain	Residue	Details
A	SER296
B	SER296
C	SER296
D	SER296

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