4G7V

Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.5 A)

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GO(遺伝子オントロジー)由来の情報

鎖名GO(遺伝子オントロジー)id名前空間内容
S0016021cellular_componentintegral component of membrane
S0005216molecular_functionion channel activity
S0016314molecular_functionphosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
S0004725molecular_functionprotein tyrosine phosphatase activity
S0008138molecular_functionprotein tyrosine/serine/threonine phosphatase activity
S0046856biological_processphosphatidylinositol dephosphorylation
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PDBデータベースに由来する情報

site_id残基数詳細
AC12BINDING SITE FOR RESIDUE LDA H 301
鎖名残基
HSER31
HTYR55

AC24BINDING SITE FOR RESIDUE CL L 301
鎖名残基
LPRO59
LPRO59
LARG61
LARG61

AC310BINDING SITE FOR RESIDUE SIN L 302
鎖名残基
LSER30
LSER65
LGLY66
LSER67
LGLY68
LASP70
LPHE71
SASP204
SVAL207
SGLN208

AC45BINDING SITE FOR RESIDUE LDA L 303
鎖名残基
LSER28
LSER30
STYR200
SASP204
SLDA301

AC55BINDING SITE FOR RESIDUE LDA S 301
鎖名残基
LSER53
LLDA303
SGLN208
SGLU209
STHR210

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「HETATM」原子の座標から抽出されたリガンド結合部位

site_id残基数詳細
LDA_4g7v_H_30112LAURYL DIMETHYLAMINE-N-OXIDE binding site
鎖名残基ligand
HSER31-SER32LDA: LAURYL DIMETHYLAMINE-N-OXIDE
HTYR54-TYR55LDA: LAURYL DIMETHYLAMINE-N-OXIDE
HTYR100-SER101LDA: LAURYL DIMETHYLAMINE-N-OXIDE
HTYR104LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SGLU217-LEU218LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SVAL220-LEU221LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SLEU224LDA: LAURYL DIMETHYLAMINE-N-OXIDE

LDA_4g7v_L_30318LAURYL DIMETHYLAMINE-N-OXIDE binding site
鎖名残基ligand
LSER28-SER30LDA: LAURYL DIMETHYLAMINE-N-OXIDE
LPHE92-TYR93LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SVAL195-THR197LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SPHE199-TYR200LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SASP204LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SVAL207LDA: LAURYL DIMETHYLAMINE-N-OXIDE
STHR210LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SALA212LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SLEU215-GLY216LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SLEU218-VAL219LDA: LAURYL DIMETHYLAMINE-N-OXIDE

SIN_4g7v_L_30216SUCCINIC ACID binding site
鎖名残基ligand
LSER28SIN: SUCCINIC ACID
LSER30-SER31SIN: SUCCINIC ACID
LALA51SIN: SUCCINIC ACID
LSER65-PHE71SIN: SUCCINIC ACID
SASP204-GLN208SIN: SUCCINIC ACID

LDA_4g7v_S_3019LAURYL DIMETHYLAMINE-N-OXIDE binding site
鎖名残基ligand
LSER52-LEU54LDA: LAURYL DIMETHYLAMINE-N-OXIDE
SGLN208-ASP213LDA: LAURYL DIMETHYLAMINE-N-OXIDE

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UniProtにおけるモチーフ・データベースPROSITEからの機能情報

site_id残基数詳細
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SwissProt/UniProtに記載されている蛋白質分子機能情報

site_id残基数詳細
SWS_FT_FI158Helical. {ECO:0000256|SAM:Phobius}.
鎖名残基詳細
SLEU38-ILE57
SLEU77-TYR94
SVAL106-LEU125

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CSAにおける酵素触媒機能の情報

site_id残基数詳細